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基于液体透镜的显微镜自动调焦技术 被引量:7

Autofocus Technology Based on Liquid Lens in Microscopic Imaging System
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摘要 本文针对生物显微镜对于自动调焦的要求,通过光学仿真和实验验证了液体镜头技术在生物医学显微镜自动调焦方面的应用。首先基于液体镜头的分类介绍了市场上具有代表性的Varioptics和Optotune lens公司的液体镜头产品的原理和特点,通过对比这两种液体透镜的特点,选择Optotune公司的液体镜头作为显微镜自动调焦装置。其次,本文根据液体镜头的光学参数,将其集成到现有的显微镜系统中,使用Zemax软件模拟了系统的变焦过程,并仿真了系统的光学性能。最后对Optotune液体镜头在生物显微镜上的调焦功能进行了实验验证,并获取了系统在不同焦距的图像。实验结果表明,液体透镜可以使系统的景深扩展1 mm以上,并且保持了良好的成像质量。基于液体镜头技术的显微镜自动调焦技术具有结构紧凑,低成本,快速调焦的特点,同时也能满足较高的成像质量。 With the development of microscopic imaging technology, the autofocus method has been adopted more widely. An innovative autofocus solution is presented based on liquid lens used in microscope imaging system through optical simulation and experiment. Firstly, two commercialized liquid lens are discussed on its principle and application, and Optotune lens was chosen as the autofocus device for microscopic imaging system. Secondly, the liquid lens is integrated into the system design and the optical performances are simulated. Finally, the experiment is carried out in order to evaluate the functionality and performance of the integrated system. Experiment results show that the depth of field of the system can be extended to 1mm while maintain good image quality. The autofocus technology based on liquid lens has the advantage of compact design, fast focusing, and low cost without compromising its optical performance.
作者 张祥翔
出处 《光电工程》 CAS CSCD 北大核心 2015年第10期37-42,共6页 Opto-Electronic Engineering
关键词 液体透镜 显微系统 自动调焦 生物医学成像 liquid lens microscope autofocus medical imaging
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参考文献10

  • 1昊冬冬.全自动尿沉渣分析仪的显微自动调焦系统设计与实现[D].武汉:武汉理工大学,2012:30-52.
  • 2张鹰,张新,史广维,王超,王钰.液体透镜在变焦系统中的应用[J].中国光学,2013,6(1):46-56. 被引量:23
  • 3石广丰,杨彬,史国权,徐远哲.高速变焦液体透镜的发展动态综述[J].红外技术,2014,36(10):777-781. 被引量:10
  • 4Mermillod-Blondin A, McLeod E, Arnold C B. High-speed varifocal imaging with a tunable acoustic gradient index of refractionlens [J]. Optics Letters(S0146-9592), 2008, 33: 2146-2148.
  • 5Optotune EL-10-30 datasheet [EB/OL]//http: www.optottme.com, 2015-03-20.
  • 6张运波,侯文玫,郑继红.采用变焦液体透镜的共焦检测系统的设计与仿真[J].应用光学,2012,33(1):14-18. 被引量:5
  • 7Grewe B F, Voigt F F, van't HoffM, et al. Fast two-layer two-photon imaging of neuronal cell populations using an electrically tunable lens [J]. Biomedical Optics Express(S2156-7085), 2011, 2(7): 2035-2046.
  • 8Blum M, Biaeler M, Grltzel C, et al. Compact optical design solutions using focus tunable lenses [J]. SPIE Optical Design and Engineering lV, Proeeedings, 2011, 8167: 5210-5215.
  • 9Fahrbach F O, Voigt F F, Schmid B, Helmchen F, et al. Rapid 3D light-sheet microscopy with a tunable lens [J]. Optical Express(S1094-4087), 2013, 21(18): 21010-21026.
  • 10许盛,李见为.高级显微镜智能化自动调焦系统的研究及实现[J].光学仪器,2000,22(5):22-26. 被引量:3

二级参考文献33

  • 1卢威,傅丹鹰,孙燕萍,陶家生.液体镜头技术应用于空间探测的初步探讨[J].航天返回与遥感,2007,28(1):25-29. 被引量:2
  • 2霍勒DF.光学仪器及其应用[M].北京:机械工业出版社,1988..
  • 3普拉特WK.数字图像处理学[M].北京:科学出版社,1984..
  • 4袁详辉.固体图像传感器及其应用[M].重庆:重庆大学出版社,1994..
  • 5Campbell. K, Fainman Y, Groisman A. Pneumatically actuated adaptive lenses with millisecond response time[J]. Applied Physics Letters, 2007, 91(17): 171111-171113.
  • 6Zhang D Y, Justis N, Lo Y H. Fluidic adaptive lens of transformable lens type[J]. Applied Physics Letters, 2004, 84(21 ): 4194-4196.
  • 7Kuiper S, Hendriks B. Variable-focus liquid lens for miniature cameras[J] Applied Physics Letters, 2004, 85:1128-1130.
  • 8Von Waldkirch, M, Lukowicz P, Ster G T. Oscillating fluid lens in coherent retinal projection displays for extending depth of focus[J]. Optics Commun, 2005, 253: 407-418.
  • 9Kuiper S, Hendriks B H W. Variable-focus liquid lens for miniature cameras[J]. Applied Physics Letters, 2004, 85:1128-1130.
  • 10Joseph D. Olles,1 Michael J. Vogel. Optical performance of an oscillating, pinned-contact double droplet liquid lens[J]. Optics Express, 2011, 19(20) 19399-19406.

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