摘要
目的比较经尿道钬激光膀胱肿瘤切除术(HOLBT)与等离子电切术(PKRBT)的临床效果,探讨这两种手术方式在治疗膀胱肿瘤的适应证、疗效、安全性及并发症等方面的优劣。方法将2011年3月-2013年3月纳入研究范围的100例膀胱肿瘤患者随机分成2组,每组50例,分别行HOLBT和PKRBT。记录两组患者术前一般病史资料,伴发疾病,术前实验室检查,术前膀胱肿瘤位置、大小、数目和病理情况,手术时间及其他术中指标,术后实验室检查,术后肉眼血尿时间、膀胱冲洗时间、留置尿管时间及住院时间和术后并发症的情况,以及术后3、6、12个月时随访情况。对两组各项指标进行对比、分析及统计学处理。结果两组患者术前各项指标差异无统计学意义(P>0.05),手术均顺利完成。术后实验室检查均无明显异常。两组之间手术时间、膀胱冲洗时间、术后尿管留置时间及术后住院时间差异均无统计学意义(P>0.05);HOLBT组仅术后肉眼血尿时间[(6.1±7.6)h]较PKRBT组[(15.3±17.2)h]短,差异有统计学意义(P<0.05)。术后3、6、12个月时门诊随访时膀胱肿瘤复发率差异无统计学意义(P>0.05)。结论 HOLBT治疗膀胱肿瘤疗效显著、过程安全、操作简便。与PKRBT相比较,术中操作均有效、安全,疗效相近,术中及术后并发症较少。
Objective To compare the clinical efficacy of transurethral plasmakinetic resection of bladder tumors（PKRBT） and holmium laser resection of bladder tumors（HOLBT）, and discuss the efficacy, safety, indication, and complications of PKRBT for the treatment of bladder tumors compared with HOLBT. Methods A hundred patients with bladder tumors were divided into two groups randomly, who were selected from patients in the Department of Urology of West China Hospital from March 2011 to March 2013. Among all the 100 cases, half of them were treated with PKRBT, and all others treated with HOBLT. The significant markers in both groups were recorded and evaluated, including the situation of before operation, during operation and after operation. The data recorded consisted of the general records of patients＇ medical background, concomitant disease, laboratory examination, and the position, amount, pathology of the tumor, total operative duration, the time of gross hematuria, the time of postoperative bladder irrigation and catheterization, the length of stay, postoperative complications and patients＇ conditions at month 3, 6, and 12 during the follow-up. Results All operations were successfully performed, and there was no significant differences between the two groups in preoperative indexes（P〉0.05）. No abnormalities were detected in the postoperative laboratory examinations. The differences in operatative duration, time of bladder irrigation, duration of indwelling catheter, and postoperative length of stay between the two groups were not significant（P〉0.05）. But the mean time of gross hematuria was significantly shorter after operation in the HOLBT patients [（6.1±7.6） hours] than in those treated with PKRBT [（15.3±17.2） hours]（P〈0.05）. There was no significant difference between the two groups in the recurrence rate 3, 6, and 12 months after operation（P〉0.05）. Conclusions HOLBT can be used safely and effectively in treating bladder tumors, and it is easy for clinical manipulation. HOLBT is as effective and safe as PKRBT with similar adverse side-effect rate within and after operation.
出处
《华西医学》
CAS
2015年第10期1877-1880,共4页
West China Medical Journal
关键词
膀胱肿瘤
钬激光
等离子电切
Bladder tumor
Holmium laser
Plasmakinetic resection
