期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

慢性丙型肝炎患者外周血DNT细胞与HCV-RNA病毒载量关系的研究 被引量：1

下载PDF
导出
摘要 丙型肝炎是由丙型肝炎病毒（hepatitis C virus,HCV）感染机体后所引起的传染性疾病。大多数的丙型肝炎患者感染后转为慢性,病毒在体内持续存在,慢性丙型肝炎是引起肝硬化和肝癌的重要原因之一。
作者 马寅芙 李首庆 刘磊 孙牧男 谭岩
机构地区 吉林省人民医院
出处 《中国实验诊断学》 2015年第10期1754-1756,共3页 Chinese Journal of Laboratory Diagnosis
基金 中青年科技创新领军人才及团队项目 吉林省肿瘤生物治疗创新团队(20140519018JH) 吉林省科技厅青年科研基金项目(20140520037JH)
关键词 丙型肝炎患者 HCV-RNA DNT细胞 细胞亚群 慢性丙型肝炎 病毒载量 移植物抗宿主病 自身免疫性疾病 感染机体 移植排斥
分类号 R512.63 [医药卫生—内科学]
  • 相关文献

参考文献19

  • 1D' aequisto F, Crompton T. CD3 q- CD4-CD8-( double negative) T cells:saviours or villains of the immune response[J]. Biochem Phar-macol, 2011,82 (4) :333.
  • 2丙型肝炎防治指南[J].中华内科杂志,2004,43(7):551-555. 被引量：106
  • 3Gao X,Cui Q,Shi X,et al. Prevalence and trer/d of hepatitis C vi- rus infection among blood donors in Chinese mainland~ a systemat- ic review and meta-analysis[J]. BMC Infect Dis, 2011,11 : 88.
  • 4Alter MJ, Kuhnert WL, Finelli L. Guidelines for laboratory testing and result reporting of antibody to hepatitis cvirus. Centers for disease control and prevention. MMWR[J].Recomm Rep, 2003, 52(RR-3) :1.
  • 5Mendez S,Reckling SK,Piccirillo CA, et al. Role for CD4 + CD25 +regulatory T ceils in reactivation of persistent leishmaniasis and control of concomitant immunity[J]. J Exp Med 2004,200:201.
  • 6Schwadron RB, Palathumpat V, Strober S. Natural suppressor ceils derived from adult spleen and thymus[J].Transplantation, 1989,48(1) : 107.
  • 7Fischer K,Voelkl S, Heymann J, et al. Isolation and characteriza- tion of human ntigen-specific TCR alphabeta + CD4 double-negative regulatory T eells[J].Blood, 2005,105 (7) CD8 2828.
  • 8Hayes SM,Li L,Love PE. TCR signal strength Influences lphabe- ta/gammadelta lineage fate[J].Immunity, 2005,22 : 583.
  • 9Landolfi MM, Van Houten N, Russell JQ, et al. CD2-CD4-CDS- lymph node T lymphocytes in MRL lpr/lpr mice are derived from a CD2 q- CD4 +CD8 +thymic precursor[J]. J Immunol, 1993, 151:1086.
  • 10Crispin JC,Tsokos GC. Human TCR - alpha beta + CD4 - CD8 - T cells can derive from CD8 q- T ceils and display an inflamma- tory effector phenotype[J]. J lmmunol, 2009,183 (7) : 4675.

二级参考文献13

  • 1Fischer K, Voelkl S, Heymann J, et al. Isolation and characterization of human antigen-specific TCR alpha beta CIM - CD8 - double-nega- tive regulatory T cells [J] . Blood, 2005, 105 (7) : 2828 -2835.
  • 2D'acquisto F, Crompton T. CD3 + CD4- CD8- (double negative) T cells : saviours or villains of the immune response [J] . Bioehem Phar- macol, 2011. 82 (4): 333-340.
  • 3Thomson CW, Lee BP, Zhang L. Double-negative regulatory T cells: non-conventional regulators [ J ] . Immunol Res, 2006, 35 ( 1 2 ) : 163 - 178.
  • 4Wang X, Yan W, Lu Y, et al. CD4 - CD8 - T cells contribute to the persistence of viral hepatitis by striking a delicate balance in immune modulation [ J ] . Cell Immunol, 2012, 280 ( 1 ) : 76 - 84.
  • 5Wu Z, Hart M, Chen T, eta/. Acute liver failure: mechanisms of immune- mediated liver injury [J] . Liver Int, 2010, 30 (6) : 782 -794.
  • 6Lehtimaki S, Lahesmass R. Regulatory T cells control immune respon- ses through their non-redundant tissue specific features [ J ] . Front Im- munol, 2013, 4: 294.
  • 7Voelkl S, Gary R, Mackensen A. Characterization of the immunoregu- latory function of human TCR-alphabeta + CD4 - CD8 - double-negative T cells [J] . Eur J Immunol, 2011, 41 (3) : 739 -748.
  • 8Su Y, Huang X, Wang S, et al. Double negative Treg cells promote nonmyeloablative bone marrow chimerism by inducing T-cell clonal de- letion and suppressing NK cell function [ J] . Eur J Immunol, 2012, 42 (5), 1216-1225.
  • 9Ford Mclntyre MS, Gao JF, Li X, et al. Consequences of double neg- ative regulatory T cell and antigen presenting cell interaction on im- mune response suppression [ J ] . Int Immunopharmacol, 2011, 11 ( 5 ) : 597 - 603.
  • 10Gao JF, Mclntyre MS, Juvet SC, et al. Regulation of antigen-express- ing dendritic cells by double negative regulatory T cells [ J ]. Eur J Im- munol, 2011,41 (9) : 2699 - 2708.

共引文献111

同被引文献9

二级引证文献6

中国实验诊断学
2015年 第10期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部