摘要
目的:研究牙龈环切辅助牙周炎患牙正畸压低对牙周炎患牙PGE2、ALP与预后的影响。方法:选取于本院行牙周炎行患牙正畸治疗的患者100例为研究对象,随机分为治疗组和对照组,每组各50例。所有患者均进行基础治疗,治疗组联合牙龈环切治疗,对照组不行牙龈环切。并对两组的牙周状况、咀嚼效能、IL-1β及PGE2水平、ALP水平及牙根长、CEJ-AC、冠根比、ABLR变化进行比较。结果:治疗组治疗后牙齿的稳定性增加、移位牙复位、牙周袋明显变浅,牙龈未见炎症,与对照组比较,差异均具有统计学意义(P<0.05);与治疗前相比,对照组经过基础治疗后咀嚼效能明显提高,治疗组治疗后,与对照组及治疗前咀嚼效能明显提高,差异均具有统计学意义(P<0.05);牙龈环切前,两组PGE2及IL-1β水平均较低,治疗后1hPGE2及IL-1β逐渐增加,两组差异逐渐加大,24h最高,此后开始缓慢降低,并在168h水平相当。治疗后,两组ALP水平均明显降低,且治疗组降低程度高于对照组,差异均具有统计学意义(P<0.05);在牙根长、CEJ-AC、冠根比、及ABLR方面,治疗组治疗效果强于对照组,差异具有统计学意义(P<0.05)。结论:牙龈环切辅助患牙正畸可提高周围牙槽骨高度,改善牙周支持,促进IL-1β、PGE2及ALP恢复正常水平,提高疗效,有利于预后。
Objective：To investigate the effects of supportive circumferential supracrestal fibrotomy on PGE2,ALP levels in periodontitis patients undergoing dental orthodontic treatment.Methods：A total of 100 periodontitis patients undergoing dental orthodontic treatment were randomly divided into treatment group and control group with 50 cases in each group.All patients were treated with basic therapy,but the treatment group also underwent supportive circumferential supracrestal fibrotomy.The periodontal status,chewing efficiency,IL-1β,PGE2,,ALP,root length,CEJ-AC level,ratio of dental crown and root length,changes in ABLR changes were compared betwen the two groups.Results：After treatment,tooth stability of the treatment group increased,location of shifted tooth was restored,periodontal pocket became shallow,gingivitis recovered showing significant difference comparing with that of the control group（P〈0.05）.Comparing with status before treatment,masticatory efficiency of both groups were improved significantly but the efficiency of treatment group was significant better than that of the control group（P〈0.05）.Before undergoing the treatment,PGE2 and IL-1βlevels of both groups were decreased.After treatment,PGE2 and IL-1βlevels increased gradually,but the difference in these levels between the two groups became larger at the same time,the largest deference was observed at 24 hafter that,it became smaller and reached almost the same level at 168 h.After treatment,the ALP level decreased gradually but the decrease of the treatment group was significant obvious than that of the control group（P〈 0.05）.Regarding to root length,CEJ-AC level,ratio of dental crown and root length,the efficiency of the treatment group was super than that of the control group.Conclusion：Supportive circumferentialsupracrestal fibrotomy can help to improve the height of the surrounding alveolar bone and periodontal support,it can also promote the recovery of IL-1PGE2,ALP,thus is good for the prognosis.
出处
《海南医学院学报》
CAS
2015年第12期1730-1732,1736,共4页
Journal of Hainan Medical University
基金
国家科技支撑计划资助项目(2008BAI68B06)~~
关键词
牙龈环切
正畸压低
牙周炎
PGE2、ALP
Circumferential supracrestal fibrotomy
Orthodontic depression
Periodontitis
ALP
PGE2
