摘要
目的:对慢性肾小球肾炎血尿患者进行中医辨证分型,观察不同证候患者尿红细胞检出情况及异常红细胞检出率,探讨不同证候与尿红细胞形态的相关性。方法:选取慢性肾小球肾炎患者130例,根据中医辨证将患者分为不同证型,探讨各个证型患者分布情况,并分别对5组患者血尿中的异形红细胞含量及形态进行探讨。结果:1)本证以脾肾阳虚证患者占比例最多,占所有患者的48.5%,差异有统计学意义(P<0.05);2)脾肾阳虚证患者异常红细胞百分比明显高于其它几组,差异有统计学意义(P<0.05),剩余4组间差异无统计学意义(P>0.05);3)脾肾阳虚证与肝肾阴虚证患者尿棘形红细胞占百分比明显高于其它3组患者,差异有统计学意义(P<0.05);4)脾肾气虚证患者中,环红细胞含量最高,其次为正红细胞,棘红细胞含量最少,脾肾阳虚证患者中,棘红细胞含量最少;肺肾气虚证患者大红细胞含量最多,棘红细胞含量最少;肝肾阴虚证患者正常红细胞含量最高;气阴两虚证患者,小红细胞含量最多,其次为正常红细胞,棘红细胞含量最少。结论:不同证候的肾小球肾炎患者血尿中异常红细胞水平不同,形状也各自有各自特点,根据不同形状异常红细胞所占比例可以对慢性肾炎患者中医辨证进行辅助诊断。
Objective： To observe the urine red blood cell detection and abnormal red blood cell detection rate of different types of syndrome of chronic glomerular nephritis patients with hematuria,discuss the correlation of TCM syndromes and red cell morphology. Methods： 130 patients with chronic glomerular nephritis were divided into five groups for spleen and kidney qi deficiency syndrome,spleen and kidney yang deficiency syndrome,liver and kidney yin deficiency syndrome,both qi and yin deficiency syndrome,lung and kidney deficiency syndrome according to differentiation of syndromes in TCM. To analyze the abnormal changes of urine red blood cell. Results： 1） The most common- seen syndrome was spleen- kidney yang deficiency,it accounted for48. 5%; differences were statistically significant（ P〈0. 05）. 2） Percentage of poikilocyte of spleen and kidney yang deficiency syndrome patients which was significantly higher than that of other groups（ P〈0. 05）,while there was no statistically significant difference in other four groups（ P〉0. 05）. 3） Percentage of poikilocyte of spleen and kidney yang deficiency syndrome and liver and kidney yin deficiency syndrome groups were significantly higher than those of other groups（ P〈0. 05）. 4） The amount of ring- type RBC in spleen and kidney qi deficiency syndrome group was the highest,the second was pronormoblast,and the amount of acanthocyte was the least. The anount of acanthocyte was the least in spleen and kidney yang deficiency syndrome group; the amount of macroerythrocyte was the highest and acanthocyte was the least in liver and kidney qi deficiency syndrome; the amount of normocyte was the highest in liver and kidney yin deficiency syndrome（ P〈0. 05）. The amount of microcyte was the highest and acanthocyte was the least in both qi and yin deficiency syndrome（ P〈0. 05）. Conclusion： The amount of abnormal erythrocyte are different in different type patients and the shapes are also difference,the different amount of abnormal red blood cells can auxiliary be taken as diagnose indexes for diffenentiation of syndromes in chronic glomerular nephritis patients.
出处
《中国中医药科技》
CAS
2015年第5期481-482,499,共3页
Chinese Journal of Traditional Medical Science and Technology
关键词
慢性肾小球肾炎
血尿
中医证候
红细胞形态
chronic glomerular nephritis
Chinese medicine syndromes
hematuria
erythrocytic morphous
