摘要
目的：探讨腹腔镜治疗直肠癌对机体的应激影响、安全性及近期疗效。方法选取2011年1月~2013年5月本院收治的80例直肠癌患者作为研究对象，按照随机数字表法分为观察组和对照组，各40例。观察组实施腹腔镜手术，对照组进行常规开放手术，比较两组的术后排气时间、下床活动时间、术后住院时间以及术后24 h C-反应蛋白、白细胞及白细胞介素-6水平等应激指标，统计两组围术期发生的并发症，随访2年，统计两组的2年生存率并绘制生存曲线。结果观察组的排气时间、下床活动时间及术后住院时间显著短于对照组，差异有统计学意义（P〈0.05）。观察组术后24 h的C-反应蛋白、白细胞及白细胞介素-6水平显著低于对照组，差异有统计学意义（P〈0.05）。观察组的并发症发生率显著低于对照组，差异有统计学意义（P〈0.05）。结论腹腔镜下直肠癌手术具有创伤小、术后恢复快、对患者应激刺激小、并发症少、术后生存率高等优点，值得临床推广应用。
Objective To explore the safety,short-term effect and stress affect on the body of laparoscope in the treat-ment of rectal cancer. Methods 80 cases with rectal cancer from January 2011 to May 2013 in our hospital were se-lected and divided into the observation group and the control group according to the random number table method,40 cases in each group.The observation group was given laparoscopic surgery,the control group was given conventional open surgery.The time of exhaust,ambulation time and postoperative hospital stay,the stress index of C-reactive protein after surgery in 24 hours,white blood cells and interleukin-6 level in two groups was compared,the complication of two groups was statistically analyzed.Followed up for 2 years,the survival rate of two groups was statistically analyzed and the survival curves were plotted. Results The exhaust time,ambulation time and postoperative hospital stay in the ob-servation group was shorter than that in the control group,with significant difference （P〈0.05）.The level of C-reactive protein after surgery in 24 hours,white blood cells and interleukin-6 in the observation group was lower than that in the control group,with significant difference （P〈0.05）.The incidence rate of complication in the observation group was lower than that in the control group,with significant difference （P〈0.05）. Conclusion Laparoscope in the treatment of rectal cancer has the advantages of less trauma,quicker recovery,less stress,,less complication,higher survival rate after surgery,it is worthy of promotion and application.
出处
《中国当代医药》
2015年第29期67-69,共3页
China Modern Medicine
关键词
腹腔镜
直肠癌
应激
安全性
近期疗效
Laparoscope
Colorectal cancer
Stress
Security
Short-term effect
