摘要
目的:探讨瓣膜置换术后患者出血的危险因素及药学监护要点,为降低心脏术后需要进行二次开胸手术的风险提供参考。方法:结合相关文献,分析瓣膜置换术后患者行二次开胸探查止血的出血原因,探讨更合理的药物治疗方案,并对一个具体案例提出相应的药学监护建议。结果:术前肝功能的调整,术中鱼精蛋白的合理应用和残余肝素量的有效监测,术后华法林抗凝的正确监护都可能降低类似患者的出血发生率。结论:抗凝药物的正确使用及细致的药学监护可能降低瓣膜置换术后的出血风险,避免因此导致的二次手术。
Objective: To investigate the risk factors of hemorrhage in patients after heart valve re-placement, the main points of pharmaceutical care and to provide references for reducing the risk of reex-ploration for haemostasis. Methods: On the base of pertinent literatures, the cause of bleeding was ana-lyzes in patients after valve replacement to explore more rational therapeutic regimens and provide pharma-ceutical care suggestions for a specific patient. Results: The adjustment of hepatic function preoperation, the reasonable application of protamine and effective monitoring of residual heparin during operation, and the right monitoring of warfarin postoperation can reduce the bleeding incidence in similar patients. Con-clusion: This case analysis may have certain reference value in the pharmaceutical care of similar patients.
出处
《药学与临床研究》
2015年第3期313-316,共4页
Pharmaceutical and Clinical Research
关键词
出血
二次探查
肝素
鱼精蛋白
Bleeding
Reexploration
Heparin
Protamine
