摘要
目的分析含有冷-热自身抗体的自身免疫性溶血性贫血(AIHA)患儿的血清学特点,进行血型鉴定及交叉配血。方法将3人份O型红细胞吸收患儿血清中的自身抗体(采用冷吸收的方法);2-硫基乙醇(2-Me)破坏IgM抗体。结果此例AIHA患儿血型为B+,含冷-热自身抗体,配血不相合。结论患儿冷-热自身抗体同时存在,干扰血型鉴定、影响交叉配血。紧急情况时,结合患儿病情,输血与药物联合应用,可获得良好效果。
Objective Serological characteristic analysis for patients with autoimmune hemolytic anemia（AIHA）who has cold and warm auto‐antibody when undergoing blood type and cross‐matching .Methods Choosed 3 donors of red blood cells of group O to absorb autoantibodies of the patient′s serum（by using the methods of cold absorption） and used 2‐mercaptoethanol（2‐Me） to de‐stroyed the IgM antibody .Results The patient of AIHA blood type was B＋ .There was cold and warm auto‐antibody in the pa‐tient′s serum ,and the result of cross‐matching is incompatible .Conclusion The patient′s serum contains cold and warm auto‐anti‐body which interferes blood type and cross‐matching .In emergency ,considering the patients condition ,blood transfusion combined with the drug treatment could achieve good effects .
出处
《国际检验医学杂志》
CAS
2015年第20期2975-2976,共2页
International Journal of Laboratory Medicine
关键词
冷-热自身抗体
正反定型
配血不合
输血
cold and warm auto-antibody
form-reverse blood type
incompatible
blood transfusion
