摘要
患者女,13岁。双下肢皮损伴痒痛5年余。查体:一般情况良好;臀部及双侧股内侧、膝部、小腿下段及足背对称分布红色角化性斑块,双手背散在淡红色丘疹及斑块。皮损组织病理示:表皮显著网篮状角化过度,局灶性角化不全,颗粒层增厚,棘层肥厚,真皮浅层血管周围轻度淋巴细胞浸润。诊断为进行性对称性红斑角化症。
A 13-year-old girl presented with pruritic and painful skin lesions on bilateral lower limbs for more than 5 years. Her general health was normal. Some erythematous keratotic plaques were symmetrically present on her bottocks, bilateral medial thighs, knees, lower part of legs, dorsa of feet. Scattered fleshed papules and plaques were found on the back of her hands. Histopathology showed marked hyperkeratosis with a basketweave pattern, focal parakeratosis, granulosis, acanthosis and mild perivascular infiltrate of lymphocytes in the papillary dermis. The diagnosis of progressive symmetric erythrokeratodermia was established.
出处
《中国皮肤性病学杂志》
CAS
CSCD
北大核心
2015年第11期1182-1183,共2页
The Chinese Journal of Dermatovenereology
关键词
进行性对称性红斑角化症
Progressive symmetric erythrokeratodermia