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复方枯矾散联合特比萘芬治疗湿性足癣随机平行对照研究 被引量:4

Kufan San Joint Compound Alum Terbinafine Treatment of Wet Pedis Randomized Controlled Study
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摘要 [目的]观察复方枯矾散联合特比萘芬治疗湿性足癣疗效。[方法]使用随机平行对照方法,将94例门诊患者按掷骰子法简单随机分为两组。对照组45例特比萘芬乳膏,药膏薄层均匀涂于患处,轻揉片刻,早、晚各1次。治疗组49例复方枯矾散(枯矾30g,苍术10g,滑石粉100g,硼砂粉、赤石脂各10g,苦参30g),药物混合,研磨成粉,前2周外用皮损处2次/d,后2周早外用皮损处1次,晚外用特比萘芬乳膏1次。连续治疗7d为1疗程。观测临床症状、真菌清除率、不良反应。连续治疗4疗程,判定疗效。[结果]治疗组痊愈34例,有效12例,无效3例,总有效率93.86%。对照组痊愈24例,有效11例,无效10例,总有效率77.87%。治疗组疗效优于对照组(P<0.05)。真菌清除率治疗组优于对照组(P<0.05)。[结论]复方枯矾散联合特比萘芬治疗湿性足癣疗效满意,无严重不良反应,值得推广。 [Objective]To observe the effect of Kufan San Joint Compound alum terbinafine treatment.[Methods]Randomized parallel controlled method,94 outpatients law by simple dice randomly divided into two groups.The control group 45 cases of terbinafine cream,cream evenly thin layer onto the affected area,gently massage a moment,morning and evening,the 1st.Compound treatment group,49 cases of alum powder(Kufan 30 g,Cangzhu 10 g,Huashifen 100 g,Pengshafen,Chishizhi 10 g,Kushen 30g),pharmaceutical compounding,ground into powder,two weeks before external lesions at 2 times/d,after two weeks early external lesions at one time,late topical terbinafine hydrochloride cream 1 times.7d for a course of continuous treatment.Observation of clinical symptoms,fungal clearance rate,adverse reactions.4 courses of continuous treatment,to determine efficacy.[Results]The cure 34 cases,effective 12 cases,3 cases,the total efficiency of 93.86%.The control group recovered 24 cases,effective in 11 cases,10 cases,the total efficiency of 77.87%.Treatment group than the control group(P〈0.05).Fungal clearance rate in treatment group than the control group(P〈0.05).[Conclusion]Compound alum powder combined terbinafine treatment satisfaction wet Pedis effect,no serious adverse reactions,is worth promoting.
出处 《实用中医内科杂志》 2015年第10期122-124,共3页 Journal of Practical Traditional Chinese Internal Medicine
关键词 湿性足癣 湿脚气 复方枯矾散 特比萘芬 真菌清除率 中西医结合治疗 随机平行对照研究 wet pedis wet beriberi Fufang Kufan san terbinafine fungal clearance integrative medicine randomized controlled trial in parallel
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