摘要
老年甲状腺功能减退（简称甲减）是常见的内分泌疾病，尤其常见于老年女性。由于其起病隐匿，甲减症状与机体老化表现相似，临床易于漏诊。甲减最常见病因是自身免疫性甲状腺炎。老年患者伴随疾病多、合并用药多，因此老年甲减的诊断和治疗具有一定的特殊性。老年甲减的首选药物是左甲状腺素钠（L-T4），服用时要从小剂量起始，而后缓慢增加剂量，调整用药期间应密切监测甲状腺功能，剂量稳定后定期监测甲状腺功能。对于老年亚临床甲减患者是否需要治疗尚存争议。
Hypothyroidism is a common endocrine disease in the elderly, and occurs more frequently in aged women. Because of its insidious onset （hypothyroidism-associated symptoms are very similar to those of aging process）, hypothyroidism is easy to be missed in the diagnosis for the elderly people. Its most common cause is autoimmune thyroiditis. However, coexisting chronic illness and polypharmacy in the elderly make the diagnosis and subsequent management challenging. Synthetic L-thyroxine is the drug of first choice for senile hypothyroidism, starting from a low dose regimen followed by slowly increasing. Thyroid function should be closely monitored during dose adjustment, and needs to be regularly monitored even after stable dose. Indications for treatment of subclinical hypothyroidism in the elderly patients are controversial.
出处
《中华老年多器官疾病杂志》
2015年第10期724-727,共4页
Chinese Journal of Multiple Organ Diseases in the Elderly
