摘要
目的了解来宾市抗菌药物致不良反应发生的特点与一般规律,以减少或避免药物不良反应（ADR）的发生,进一步促进临床合理用药。方法对来宾市2013~2014年抗菌药物不良反应监测中心收集的ADR报告进行汇总分析。结果3334例抗菌药物ADR报告中,年龄≤10岁的儿童发生率最高,占619例,占20.31%;头孢菌素类居首位1177例,占35.30%;其次为喹诺酮类791例,占23.73%;ADR涉及的器官或系统及临床表现主要为皮肤及其附件损害1878例,占56.33%,其次是消化系统损害573例,占11.01%。结论要充分了解抗菌药物的特性、注意事项及患者有无过敏史,在操作过程中严格遵守操作规程,避免抗菌药物不良反应的发生。
Objectives To investigate the characteristics and regularities of adverse drug reactions（ ADR） induced by anti-infective drugs and the general law of the city of Liuzhou,in order to reduce or avoid the occurrence of ADR,further promote the clinical rational drug use. Methods Tthe antibiotic drug adverse reaction of 2011 ~ 2013 in Laibin city（ ADR） monitoring center ADR reports collected were classified and analyzed. Results 3334 cases of antimicrobial agents in the ADR report,more than 10 children was the highest,accounted for 619 cases,accounting for 20. 31%; cephalosporins ranked first in 1177 cases,accounting for35. 30%; followed by quinolones in 791 cases,accounting for 23. 73%; ADR organs or systems involved and the main clinical manifestations were the damage of skin and its appendages in 1878 cases,accounted for 56. 33%,followed by 573 cases of digestive system damage,accounted for 11. 01%. Conclusions To fully understand the antimicrobial properties,matters needing attention and the patients had no history of allergy,strictly abide by the rules in the process of operation,to avoid the occurrence of adverse drug reactions of antibiotics for medical worker.
出处
《中国老年保健医学》
2015年第5期51-53,共3页
Chinese Journal of Geriatric Care
关键词
药品不良反应
抗感染药
合理用药
Adverse drug reactions
Anti-infectious agent
Rational administration
