Toll样受体在过敏性疾病、感染性疾病及肿瘤中的研究进展
摘要
先天性免疫是机体抵御病原体入侵和维持自体稳态的一个重要防御机制。Toll样受体作为先天性免疫机制中的重要受体分子,被认为在多个免疫反应相关的信号通路中起关键作用。Toll样受体家族成员能识别病原信号分子,激活机体免疫系统。然而,在不同疾病中,Toll样受体的激活或抑制将发挥截然不同的作用。本文重点阐述了Toll样受体在过敏性疾病、感染性疾病和肿瘤中的研究进展,并讨论了Toll样受体及相关药物在这些疾病中的应用。
出处
《医学研究杂志》
2015年第10期5-7,11,共4页
Journal of Medical Research
基金
国家自然科学基金青年科学基金资助项目(81402289)
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