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氯沙坦对糖尿病肾病患者尿足细胞排泄的影响

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摘要 目的:观察氯沙坦对糖尿病肾病患者尿足细胞排泄的干预效果.方法:选择本院于2013年1月-2013年6月收治的糖尿病肾病30例作为研究对象,作为观察组,经洗脱期后给予氯沙坦50mg/d,时间8周,继续以氯沙坦100mg/d,维持8周;选择同期来我院体检健康志愿者30例作为对照组,采取间接免疫荧光镜方法检测尿足细胞进行比较.结果:观察组尿足细胞检出率为80.0%,尿足细胞数(2.51±0.36)个/ml,与对照组比较差异具有显著统计学意义,P〈0.05;糖尿病肾病患者治疗8周,治疗16周后尿足细胞数分别为(1.46±0.33)个/ml、(0.67±0.29)个/ml,与洗脱期后比较差异具有显著统计学意义,P值均〈0.05.结论:氯沙坦治疗可有效降低糖尿病肾病患者尿足细胞排泄率,对保护肾功能具有重要价值.
作者 王念华
出处 《中国伤残医学》 2015年第22期37-38,共2页 Chinese Journal of Trauma and Disability Medicine
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