期刊文献+

脑小血管病的病理学 被引量:8

Pathology of cerebral small vessel disease
原文传递
导出
摘要 脑小血管病(cerebral smal vessel disease, CSVD)占所有卒中病因的25%~30%,是血管性认知损害的主要原因。由于脑小血管不易在活体和影像学上被直接观察和研究,因此 CSVD 常被用来描述临床、认知、神经影像学和神经病理学改变的综合征,而不是重点阐述引起这些综合征的小血管管壁本身的病理学改变。文章就 CSVD,特别是其血管壁的病理学改变研究进展进行了综述。 Cerebral smal vessel disease (CSVD) accounts for 25 to 30% of al strokes. It is a main cause of vascular cognitive impairment. Because of cerebral smal vessels can not easily be directly observed and studied in vivo and on imaging, so the term CSVD is generaly used to describe a syndrome of clinical, cognitive, neuroimaging, and neuropathological changes, and not focus on the pathological changes of the smal vessel wal itself that caused these syndromes. This article reviews the advances in research on CSVD, particularly its pathological changes of vessel wals.
出处 《国际脑血管病杂志》 2015年第9期704-709,共6页 International Journal of Cerebrovascular Diseases
关键词 脑小血管疾病 血管 动脉硬化 脑淀粉样血管病 Cerebral Smal Vessel Diseases Blood Vessels Arteriosclerosis Cerebral Amyloid Angiopathy
  • 相关文献

参考文献39

  • 1Pantoni L. Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges [ J ]. Lancet Neurol, 2010, 9: 689-701.
  • 2Wardlaw JM, Smith C, Dichgans M. Mechanisms of sporadic cerebral small vessel disease: insights from neuroimaging [ J ]. Lancet Neurol, 2013, 12: 483-497.
  • 3Boiten J, Lodder J, Kessels F. Two clinically distinct lacunar infarct entities? A hypothesis [ J]. Stroke, 1993, 24: 652-656.
  • 4O'Sullivan M, Lythgoe DJ, Pereira AC, et al. Patterns of cerebral blood flow reduction in patients with ischemic leukoaraiosis [ J ]. Neurology, 2002, 59: 321-326.
  • 5Terborg C, Gora F, Weiller C, et al. Reduced vasomotor reactivity in cerebral microangiopathy : a study with near-infrared spectroscopy and transcranial Doppler sonograpby [ J ]. Stroke, 2000, 31 : 924-929.
  • 6Ringelstein EB, Nabavi DG. Cerebral small vessel diseases: cerebral microangiopathies [ J] . Curt Opin Neurol, 2005, 18: 179-188.
  • 7Arboix A, Marti-Vllalta JL. Lacunar stroke[ J ]. Expert Rev Neuroth- er. 2009.9: 179-196.
  • 8脑小血管病诊治专家共识组.脑小血管病的诊治专家共识[J].中华内科杂志,2013,52(10):893-896. 被引量:143
  • 9Wardlaw JM, Smith EE, Biessels GJ, et al; STandards for Reporting Vascular changes on nEuroimaging (STRIVE vl ). Neuroimaging standards for research into small vessel disease and its contrution to ageing and neurodegeneration[ J]. Lancet Neurol, 2013, 12: 822-838.
  • 10Yao M, Herv6 D, Jouvent E, et al. Dilated perivascular spaces in small-vessel disease: a study in CADASIL[ J]. Cerebrovasc Dis, 2014, 37: 155-163.

二级参考文献3

共引文献142

同被引文献59

引证文献8

二级引证文献51

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部