摘要
脑小血管病(cerebral smal vessel disease, CSVD)占所有卒中病因的25%~30%,是血管性认知损害的主要原因。由于脑小血管不易在活体和影像学上被直接观察和研究,因此 CSVD 常被用来描述临床、认知、神经影像学和神经病理学改变的综合征,而不是重点阐述引起这些综合征的小血管管壁本身的病理学改变。文章就 CSVD,特别是其血管壁的病理学改变研究进展进行了综述。
Cerebral smal vessel disease (CSVD) accounts for 25 to 30% of al strokes. It is a main cause of vascular cognitive impairment. Because of cerebral smal vessels can not easily be directly observed and studied in vivo and on imaging, so the term CSVD is generaly used to describe a syndrome of clinical, cognitive, neuroimaging, and neuropathological changes, and not focus on the pathological changes of the smal vessel wal itself that caused these syndromes. This article reviews the advances in research on CSVD, particularly its pathological changes of vessel wals.
出处
《国际脑血管病杂志》
2015年第9期704-709,共6页
International Journal of Cerebrovascular Diseases
关键词
脑小血管疾病
血管
动脉硬化
脑淀粉样血管病
Cerebral Smal Vessel Diseases
Blood Vessels
Arteriosclerosis
Cerebral Amyloid Angiopathy