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子宫内膜浆液性乳头状癌32例临床分析 被引量:2

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摘要 目的 探讨子宫内膜浆液性乳头状癌(UPSC)的临床特点、病理特征,以提高对该疾病的认识.方法 回顾性分析本院32例UPSC患者的临床病理资料.结果 32例UPSC患者中位发病年龄66岁,所有患者无不孕、多囊卵巢综合征病史,无长期接触雌激素类药物;患者肥胖(BMI> 30 kg/m2)占6.25%,合并高血压占18.75%、糖尿病占6.25%;临床表现为阴道不规则流血患者占78.13%;Ⅲ期+Ⅳ期患者中血清CA125水平相对较高;32例中6例患者超声检查示子宫内膜厚度<5mm;术前诊刮准确率25%;术后病理子宫肌层浸润深度与淋巴结转移率无关(P>0.05);免疫组化:雌激素受体(ER)阴性占70.37%,孕激素受体(PR)阴性占81.48%,ER、PR均阴性占66.67%.结论 UPSC发病者多为绝经后妇女,且侵袭性强,恶性程度高,确诊时多为晚期;术前血清CA125水平检测对UPSC诊断有一定的参考价值;动态B超检查能发现绝经后阴道流血的妇女无宫腔内病灶,但内膜菲薄,要警惕UPSC的可能.
作者 韩辉 任允
出处 《中国医师杂志》 CAS 2015年第10期1563-1564,共2页 Journal of Chinese Physician
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参考文献7

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