摘要
目的探讨阿奇霉素联合克拉霉素治疗小儿支原体肺炎的疗效,为临床提供参考。方法选取90例小儿支原体肺炎的患者,随机分为对照组和治疗组,对照组给予阿奇霉素进行治疗,治疗组给予阿奇霉素联合克拉霉素进行治疗,比较两组患者经治疗后的临床疗效、主要生理指标复常时间及不良反应等。结果经治疗后,对照组总有效率为72.1%,治疗组为95.3%,治疗组与对照组比较差异有统计学意义(P<0.05);治疗组在体温复常时间、咳嗽消失时间、症状好转时间及住院时间较对照组差异有统计学意义(P<0.05);两组患者均未出现其他严重的不良反应。结论阿奇霉素联合克拉霉素用于治疗小儿支原体肺炎,可显著缩短生理指标复常时间,提高临床疗效,安全性较好,具有较大的临床借鉴意义。
Objective To study the efficacy of Azithromycin combined with Clarithromycin in treatment of mycoplasmal pneumonia in children,and provide reference for clinical application.Methods 90 children with mycoplasma pneumonia were selected and randomly divided into control group or treatment group.The control group received azithromycin treatment,while the treatment group was treated with azithromycin and erythromycin.The efficacy was compared between the two groups.The times to recovery of normal physiological indices and adverse reactions were observed.Results The total efficiency rate was 72.1%in the control group and 95.3% in the treatment group（P〈0.05）.There were significant differences between the two groups in the time to recovery of normal temperature,time to disappearance of cough,time to symptom remission,and length of hospital stay（P〈0.05）.No serious adverse reactions were observed in both groups.Conclusion Azithromycin combined with Clarithromycin is effective for the treatment of mycoplasma pneumonia in children,which can significantly shorten the times to recovery of normal physiological indices,improve the clinical efficacy with good safety,and has great clinical significance.
出处
《中国微生态学杂志》
CAS
CSCD
2015年第11期1313-1315,共3页
Chinese Journal of Microecology
