摘要
目的:为临床合理使用地佐辛注射液提供参考。方法:对我院骨科2014年1-12月自发呈报的80例地佐辛注射液不良反应(ADR)报告,分别从患者性别、年龄、过敏史、ADR发生时间、累及器官/系统以及临床表现等方面进行统计、分析。结果:80例病例中,40岁以上中老年女性患者ADR发生率较高(58.75%);累及器官/系统以消化系统为主(占57.50%),其次为神经系统(占16.25%)和全身性损害(占13.75%)。67例ADR发生在用药结束后2 h内;好转78例,痊愈2例。结论:临床使用地佐辛注射液时应加强用药监护,用药前仔细询问患者既往用药量及药物过敏史,且严格遵循药品说明书的要求谨慎使用。
OBJECTIVE： To provide reference for rational use of Dezocine injection in the clinic. METHODS： 80 cases of dezo- cine-induced ADR reported by orthopedics department of our hospital during Jan.-Dec. in 2014 were analyzed statistically in terms of age, gender, clinical manifestations, etc. RESULTS ： 80 cases of dezocine-induced ADR showed that the incidence of middle-aged and elderly patients aged 40 years above was higher （58.75%）, especially women. Organs or systems involved in ADR mainly were diges- tive system （57.50%）, followed by nervous system （16.25 % ） and systemic damage reaction （13.75 % ）. 67 cases of ADR occurred within 2 h after medication; 78 cases were improved and 2 cases were cured. CONCLUSIONS ： Reasonable and safe use of dezocine is main method to prevent and reduce ADR in medical institutions, and is also the important guarantee of patient＇s physical and men- tal health and life safety.
出处
《中国药房》
CAS
北大核心
2015年第32期4521-4522,共2页
China Pharmacy
