摘要
目的观察中医内外治法治疗干眼的疗效。方法 2009年1月至2012年12月门诊收集符合入组标准的干眼患者61例,随机分为中药组和西药组。中药组予中药眼周穴位涂擦和汤剂熏服治疗,西药组予0.1%玻璃酸钠滴眼液和四环素可的松眼膏,滴涂结膜囊。总疗程8周,观察两组患者治疗前后的临床疗效及症状评分、角膜荧光素染色(FL)、泪液分泌试验(SIT),泪膜破裂时间(BUT)、眼压(IOP)的变化。结果中药组32例,治愈6例,好转24例,无效2例,总有效率93.75%;西药组29例,治愈3例,好转15例,无效11例,总有效率62.07%,两组差异有统计学意义(P<0.05)。治疗8周后中药组各观察指标均好于治疗前(P<0.05),也好于西药组(P<0.05)。西药组症状评分、FL、BUT好于治疗前(P<0.05)。两组治疗前后IOP无明显变化。结论中医内外治法可缓解干眼患者症状,改善FL、SIT、BUT。
OBJECTIVE To observe the effect of internal and external treatment of Chinese medicine on dry eye. METHODS From January 2009 to December 2012, 61 dry eye patients were randomly divided into traditional Chinese medicine group and western medicine group. Traditional Chinese medicine group was treated with tradition- al Chinese medicine, eye acupuncture points rubbing and fumigation with TCM decoction. Western medicine group received 0.1% of Sodium Hyaluronate Eye Drops and tetracycline and cortisone eye ointment, drop coating conjunc- tival sac, the total course of 8 weeks was observed before and after treatment on clinical curative effect and symptom score, corneal ftuorescein staining （FL） Schirmer I test （SIT）, tear film break-up time （BUT）, intraocular pressure （lOP） changes. RESULTS There were 32 cases in Chinese medicine group, 6 cases with excellent effect, 24 cases better, 2 cases invalid, and the total effective rate was 93.75%; There were 29 cases in western medicine group , 3 cases with excellent effect, 15 cases better, 2 cases invalid, and the total effective rate was 62.07%, The total curative effect of both groups showed significant difference （P〈0.05）. After 8 weeks＇ treatment, the observation index of Chi- nese medicine group was better than that before treatment （P〈0.05）, and the western medicine group （P〈0.05）. Symptoms score, FL and BUT were all better than before treatment and in the western medicine group （P〈0.05）. There was no significant change in lOP before and after treatment in the two groups. CONCLUSIONS Internal and external treatment of Chinese medicine could relieve symptoms of patients with dry eyes and improve FL, SIT, BUT.
出处
《中国中医眼科杂志》
2015年第5期347-350,共4页
China Journal of Chinese Ophthalmology
关键词
中医内外治
干眼
眼压
internal and external treatment of traditional Chinese medicine
dry eye
intraocular pressure
