摘要
目的 本文旨在研究微波消融治疗原发性肝癌的安全性、局部控制率及近期疗效. 方法 从2006年1月-2013年1月收集了187例肝癌患者,共209个病灶. 其中有112个为邻近肺、膈肌、腹壁、结肠、胃和胆囊区的病灶. 对以上209个病灶进行微波消融治疗,病灶平均直径为3.92 cm. 消融治疗后一个月行增强CT检查,术后每三个月对患者的影像学资料、肝功能、AFP水平及生活质量进行随访,评价其有效性. 结果 186个病灶达到完全消融,完全消融率为88 .99%. 对于〈3 cm的病灶完全消融率可达100%. 23个病灶消融后出现局部肿瘤进展. 17例患者出现临床轻度并发症,轻微并发症发生率约为5.82%. 在本研究中未出现死亡及其他严重并发症. 结论 对于〈5 cm的肝癌病灶,包括对位于特殊危险区域的肝癌病灶进行微波消融是安全可行的;尤其是对于〈3 cm的小肝癌患者,微波消融可以显著延长患者生存期.
Objective To evaluate the safety and local control rate and short term survival status of the treatment for primary liver cancer by microwave ablation.Methods From January 2006 to January 2014,a total of 209 lesions in which the average diameter was 3.92 cm in 187 patients was performed the microwave ablation therapy.There were 12 lessions adjacent to lung,diaphragm,abdominal wall,stomach,colon and gallbladder area. Enhanced CT examination was performed one month after ablation and the imaging data,liver function,AFP level and quality of life were followed up every three month to evaluate the effectiveness.Results 88.99 percent of le-sions achieved complete elimination after an average 1.35 times ablation.The completed elimination ratio for small lesions less than 3 cm was up to 100%.Local tumor progression occurred in 23 lesions.Seventheen patients had mild complications.The slight complication rate was about 5.82%.Death and other serious complications did not occur in this study.Conclusion Microwave ablation is safe and feasible for the lesions of liver cancer with live cancer less than 5 cm,which is located in the special dangerous area of liver cancer.Microwave ablation can significantly prolong the survival time of patients,especially for small HCC patients with 〈3cm.
出处
《实用肿瘤学杂志》
CAS
2015年第5期395-399,共5页
Practical Oncology Journal
基金
黑龙江省卫生厅科教处资助项目（2005-58）
关键词
肝癌
微波消融
CT引导
Primary liver cancer
Microwave ablation
CT-guided
