摘要
目的：研究中药辨证结肠灌肠治疗痛风性肾病的临床效果,为临床痛风性肾病的治疗提供依据。方法：对2010年2月~2012年10月我院入院治疗的124例痛风性肾病患者进行了研究,随机分为两组,在基础治疗之上,对照组采用别嘌醇进行治疗,治疗组采用别嘌醇联合中药灌肠进行治疗,比较两组患者治疗前后的肾功能指标、尿液相关指标以及临床总有效率。结果：治疗组患者的UA、SCr以及BUN等指标明显低于对照组,差异有统计学意义（P〈0.05）;治疗组患者尿PRO、尿RBC等指标的水平明显低于对照组,差异有统计学意义（P〈0.05）;治疗组中医证候临床总有效率为87.1%,明显高于对照组72.6%,两组比较差异明显,有统计学意义（P〈0.05）;治疗组西医诊断临床总有效率为85.5%,明显高于对照组69.4%,两组比较差异明显,有统计学意义（P〈0.05）。结论：中药辨证结肠灌肠治疗痛风性肾病临床效果显著,改善患者临床指标更明显,临床总有效率更高,值得临床推广应用。
Objective： To study the clinical effect of traditional medicine clyster with enema colon combination in the treatment of gouty nephropathy. Methods： 124 patients with gouty nephropathy from Feb 2010 to Oct 2012 were randomly divided into treatment group and controlled group,all the patients were treated with based therapy and the patients in the controlled group were treated with allopurinol,the patients in treatment group was received with allopurinol / enema colon. Renal function,urine related indicators were measured and the clinical effect was compared. Results： The UA,Scr,BUN,PRO and RBC in urine of the treatment group were lower than the controlled group,the differences were statistically significant（ P〈0. 05）; the total effective rate of traditional Chinese medicine symptom of the treatment group was 87. 1%,and the rate of the controlled group was72. 6%. the differences were statistically significant between the two groups（ P 0. 05）,the total effective rate of treatment group was 85. 5%,and the rate of the controlled group was 69. 4%,the differences were statistically significant between the two groups（ P〈0. 05） Conclusion： The combination therapy shows satisfactory clinical efficacy in the treatment of gouty nephropathy,the index are significant improved,and it is worthy of clinical use.
出处
《四川中医》
2015年第11期54-56,共3页
Journal of Sichuan of Traditional Chinese Medicine
关键词
中药灌肠
痛风性肾病
别嘌呤
临床观察
TCM clyster
Gouty nephropathy
Allopurinol
Clinical observation
