摘要
【目的】探讨颈动脉结构形态学及血流动力学超声检查在缺血性脑血管病中早期的诊断价值。【方法】选择缺血性脑血管病患者150例，其中脑梗死42例，短暂性脑缺血发作（Transient Ischemic Attack，TIA）108例（TIA组），另选择50例非脑血管病患者作为对照组；采用彩色多普勒超声技术检测三组受试者颈总动脉（common carotid artery，CCA）、颈内动脉（Internal Carotid Artery，ICA）和椎动脉（Vertebr alartery，VA）内一中膜厚度（Intima media thickness，IMT）、斑块，并测量各组收缩期峰值血流速度（PSV）、舒张末期血流速度（EDV）、血管阻力指数（resistive index，RI）、血管搏动指数（pulsative index，PI）、升支斜率／降支斜率（S1／S2）指标。【结果】脑梗死组CCA中IMT、斑块检出率均显著高于TIA组和对照组（P〈0．05），TIA组与对照组两组各段IMT及斑块检出率比较差异无统计学意义（P〉0．05）。对照组、脑梗死组、TIA组CCA、ICA、VA中PSV、EDV、S1／s2呈下降趋势，RI、PI呈上升趋势；对照组PSV、EDV、S1／$2显著高于脑梗死组和TIA组，PI、RI显著低于脑梗死组和TIA组（P〈0．05），脑梗死组PSV、EDV、S1／S2显著高于TIA组，PI、RI显著低于TIA纽（P〈0．05）。【结论】颈动脉结构形态学检查能够为脑梗死早期诊断提供依据，血流动力学检查则有助于判断TIA；超声检查颈动脉结构及血流动力学可作为早期诊断缺血性脑血管病的指标。
[Objective]To explore the ultrasonic examination of carotid structure and hemodynamics in early diagnosis of ischemic cerebrovascular disease.[Methods]One hundred and fifty cases of ischemie cerebrovascular disease were selected as research object, among which 42 cases with cerebral infarction, 108 case with TIA （Transient Ischemic Attack） ;another 50 patients with non cerebrovascular disease as the control group. Color Doppler ultrasound was used to detect the carotid artery CCA, ICA and VA, IMT and the plaque in the three groups , The systolic peak flow velocity （PSV）, end diastolic blood flow velocity （EDV）, index resistive （RI）, index PI （pulsative） and （S1/S2） index were measured.fResultslIMT and plaque detection rate of CCA in the cerebral infarction group were significantly higher than those in TIA group and the control group （ P 〈0.05）; each IMT segment and plaque detection rate of the TIA group and the control group had no significant difference statistically （ P 〉0.05）. EDV and PSV of CCA,ICA,VA in the control group, the cerebral infarction group and the TIA group showed a downward trend;PI,RI and S1/S2 showed upward one ; PSV, EDV of the control group were significantly higher than those of the cerebral infarction group and the TIA group（ P 〈0.05） ; PI, RI, S1/S2 were significantly lower than those of the cerebral infarction group and the TIA group （ P 〈0.05）, and PSV, EDV of the cerebral infarction group were significantly higher than those of the TIA group; PI, RI, S1/S2 were significantly lower than those in the TIA group （ P 〈0.05）. [Conclusion]Detection of carotid artery structure can provide evidence for the early diagnosis of cerebral infarction, and hemodynamics examination helps to determine the TIA. Ultrasound examination of carotid artery structure and blood flow dynamics can be used as an early diagnostic indicator for ischemic cerebrovascular disease .
出处
《医学临床研究》
CAS
2015年第10期1954-1957,共4页
Journal of Clinical Research
