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儿童轻微脑炎/脑病伴可逆性胼胝体压部病变谱系疾病临床-影像分析 被引量:11

Clinico-radiological characteristics of children with mild encephalitis/encephalopathy with a reversible splenial lesion
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摘要 目的探讨儿童轻微脑炎/脑病伴可逆性胼胝体压部病变谱系(MERS)的临床-影像特点。方法回顾性分析8例MERS患儿的临床资料。结果 8例MERS患儿临床表现为意识障碍5例,抽搐发作7例;临床症状于1周内恢复;消化道和呼吸道感染是主要的基础疾病;血钠<135 mmol/L者3例;7例患儿影像学诊断为MERSⅠ型,仅累及胼胝体压部,1例诊断MERSⅡ型,累及胼胝体压部及半卵圆中心白质;患儿于6 d至1个月内复查影像学,均恢复正常。结论 MERS表现为急性轻微脑炎/脑病的症状,为临床和影像学预后良好的一种谱系疾病。 Objectives To investigate the clinico-radiological characteristics of mild encephalitis/encephalopathy with a reversible splenial lesion(MERS) in children. Methods The clinical data from 8 children with MERS were retrospectively reviewed. Results The clinical manifestations of 8 children were 7 cases with serizures,5 cases with disturbance consciousness.The clinical symptoms disappeared within one week. The underlying diseases were mainly infections in respiratory and digestive tracts. Serum sodium levels 135 m Eq/L were observed in 3 cases. According to imaging,7 children were diagnosed MERS I with lesion only involving the splenium of the corpus callosum,one child was diagnosed MERS II with lesion extended from the splenium of the corpus callosum to the white matter of semi-oval. The lesion had completely disappeared in all children at follow-up MRI exams between 6 days and 1 month after the initial MRI. Conclusion MERS exhibits acute mild encephalitis/encephalopathy symptoms,which is a clinico-radiological syndrome with good prognosis.
出处 《临床儿科杂志》 CAS CSCD 北大核心 2015年第11期929-932,共4页 Journal of Clinical Pediatrics
基金 武汉市科技创新平台-儿童神经疾病临床医学研究中心资助项目(武科技No.2014-160)
关键词 脑病伴可逆性胼胝体压部病变谱系 磁共振成像 儿童 mild encephalitis/encephalopathy with reversible spleniallesion magnetic resonance imaging child
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参考文献13

  • 1Tada H,Takahashi J,Barkovich AJ,et al. Clinically mildencephalitis/encephalopathy with a reversible splenial lesion[J]. Neurology, 2004,63(10): 1854-1858.
  • 2Takanashi J, Barkovich AJ, Shiihara T, et al. Wideningspectrum of a reversible splenial lesion with transientlyreduced diffusion [J]. AJNR Am J Neuroradiol, 2006,27(4): 836-838.
  • 3赵立荣,吴晔,郭芒芒,肖江喜,姜玉武.伴胼胝体压部可逆性病变的轻度脑炎/脑病儿童病例一例并文献复习[J].中华儿科杂志,2014,52(3):218-222. 被引量:34
  • 4何燕,郭虎,卢孝鹏,郑帼.儿童可逆性胼胝体压部病变综合征的临床和影像学特点(附1例报告)[J].临床神经病学杂志,2013,26(6):448-450. 被引量:9
  • 5Okumura A, Noda E,IkutaT,et al. Transient encepha-lopathy with reversible white matter lesions in children [J].Neuropediatrics, 2006, 37(3): 159-162.
  • 6Takanashi J, Imamura A, HayakawaF,et al Differencesin the time course of splenial and white matter lesions inclinically mild encephalitis/encephalopathy with a reversiblesplenial lesion (MERS) [SI J Neurol Sci,2010, 292(1-2): 24-27.
  • 7Notebaert Al, Willems J, Coucke L, et al. Expandingthe spectrum of MERS type 2 lesions, a particular form ofencephalitis [J]. Pediatr Neurol, 2013, 48(2): 135-138.
  • 8Takanashi J. Two newly proposed encephalitis/encephalopa-thy syndromes [J]. Brain Dev, 2009,31 (7): 521- 528.
  • 9Takanashi J, Maeda M,Hayashi M. Neonate showingreversible splenial lesion [J]. Arch Neurol, 2005,62 (9):1481-1482.
  • 10Takanashi J, Tada H, Maeda M, et al Encephalopathywith a reversible splenial lesion is associated with hypona-tremia [J]. Brain Dev, 2009, 31(3): 217-220.

二级参考文献26

  • 1屈艳娟,张在鹏,徐彦红,李华刚,杨桂芳.脑后部可逆性脑病综合征2例报道并文献分析[J].武汉大学学报(医学版),2007,28(5):642-645. 被引量:8
  • 2Garcia-Monco JC, Cortina IE, Ferreira E, et al. Reversible splenial lesion syndrome (RESLES) : What's in a name? [J]. 1 Neuroimaging ,2011 ,21 : el.
  • 3Gallucci M, Limbucci N, Paonessa A, et al. Revesible focal splenial lesions[J]. Neuroradiology ,2007,49 :541.
  • 4Natsume 1,Naiki M,Yokotsuka T,et al. Transient splenial lesions in children with "benign convulsions with gastroenteritis" [J]. Brain & Development,2007 ,29 :519.
  • 5Tada H, Takanashi J, Barkovich A1, et al. Clinically mild encephalitis/ ncephalopathy with a reversible splenial lesion [J]. Nerology , 2004,63: 1854.
  • 6Takanashi J, Imamura A, Hayakawa F, et al. Differences in the time course of splenial and white matter lesions in clinically mild encephalitis/ encephalopathy with a reversible splenial lesion [J]. J Neurol Sci ,2010 ,292 :24.
  • 7Fukuda SJ, Kishi K, Yasuda KJ , et al. Rotavirus-associated encephalopathy with a reversible splenial lesion [J]. Pediatr Neurol 2009, 40:131.
  • 8Takanashi J , Tada H, Maeda M, et al. Encephalopathy with a reversible splenial lesion is associated with hyponatremia [J]. Brain & Development,2009,31 :217.
  • 9Tada H, Takahashi J, Barkovich AJ, et al. Clinically mildencephalitis/encephalopathy with a reversible splenial lesion [J].Neurology, 2004, 63:1854-1858.
  • 10Cho JS, Ha SW, Han YS, et al. Mild encephalopathy withreversible lesion in the splenium of the corpus callosum andbilateral frontal white matter[J]. J Clin Neurol, 2007,3 : 53-56.

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