摘要
macrophages in tumors are a major problem. They are dynamic and heterogeneous cells, and their differenti- ation, tissue distribution and responsiveness to stimuli are governed by distinct mechanisms. In response to certain signals, macrophages can undergo either M1- or M2-type activation, which result in two distinct functional phenotypes.
macrophages in tumors are a major problem. They are dynamic and heterogeneous cells, and their differenti- ation, tissue distribution and responsiveness to stimuli are governed by distinct mechanisms. In response to certain signals, macrophages can undergo either M1- or M2-type activation, which result in two distinct functional phenotypes.