摘要
目的:探讨健脾养胃补血方在减少结肠癌患者化疗不良反应方面的临床效果。方法:选择90例结肠癌患者作为研究对象,将其随机分为试验组和对照组,每组各45例,两组均予FOLFOX6方案化疗和常规止吐药物,对照组不给予减轻化疗不良反应的其他药物,试验组在化疗前1天开始接受健脾养胃补血方治疗。观察两组患者发生恶心、呕吐、腹泻、食欲减退、骨髓抑制等化疗不良反应发生情况。结果:试验组患者在恶心、呕吐、腹泻、食欲下降等胃肠道反应方面的发生率均明显优于对照组(P<0.05);白细胞、血红蛋白、血小板降低率均明显比对照组低,试验组患者治疗提高稳定率95.56%明显优于对照组提高稳定率82.22%(P<0.05)。结论:健脾养胃补血方可以减少结肠癌患者化疗后不良反应,对患者的康复有一定促进作用。
Objective： To investigate the clinical effect of Spleen-Tonifying Stomach-Nourishing and Blood-Nourishing Prescription in reducing side effects of chemotherapy on cancer patients. Methods： 90 cases with colon cancer were randomly divided into the experimental group and the control group,with 45 cases in each group. They were all given FOLFOX6 and standard anti-nausea drugs. The control group was not given other drugs that can reduce side effects of chemotherapy,while the experimental group was given Spleen-Tonifying Stomach-Nourishing and Blood-Nourishing Prescription the day before chemotherapy. Observe side effects of nausea,vomiting,diarrhea,anorexia,myelosuppression of the two groups. Results： The occurrence rate of gastrointestinal reaction of nausea,vomiting,diarrhea,anorexia in the experimental group was obviously lower than that in control group（ P〈0. 05）. The reduction rate of leukocyte,hematocrystallin and blood platelet of the experimental group was obviously lower than that in control group. The stable promotion rate of the experimental group（ 95. 56%） was obviously higher than that in control group（ 82. 22%）,with the difference in statistically significant（ P〈0. 05）. Conclusion： Spleen-Tonifying Stomach-Nourishing and Blood-Nourishing Prescription can reduce the side effects of chemotherapy and promote patients recovery condition.
出处
《中医学报》
CAS
2015年第11期1560-1562,共3页
Acta Chinese Medicine
基金
广东省社会发展领域引导项目(0315)
关键词
健脾养胃补血方
结肠癌
化疗不良反应
spleen-tonifying stomach-nourishing and blood-nourishing prescription
colon cancer
side effect of chemotherapy
