摘要
中医药治疗胃癌前病变有大量的临床实践,但疗效评价方法的不足严重制约了中医优势的发挥和疗效的可信度。在总结中医药治疗胃癌前病变研究现状的基础上,认为中医药治疗胃癌前病变疗效评价方法主要存在以下问题:采用复合性评价指标,疗效混淆不清;病理组织学指标评价方法不统一,影响结果可比性;胃镜下病变评价主观性强,受多种因素与条件影响;症状及中医证候评价缺乏科学的方法学依据;缺乏生活质量评价等。针对上述问题,提出疾病疗效和中医证候疗效相结合,建立以病理组织学指标为核心结合胃镜指标、患者症状、生活质量等指标的综合评价体系。
There are a lot of clinical practices of Chinese medicine treating precancerous lesions of gastric cancer（ PLGC）,but the lacks of therapeutic evaluation methods seriously restrict Chinese medicine advantages and reliability of therapeutic effect. Based on summarizing the research status of Chinese medicine treating PLGC,the authors hold that the existed problems of therapeutic evaluation methods of Chinese medicine treating PLGC mainly include the following aspects,adopting composite evaluation indexes and leading to confused effect; lack of united histopathological indexes evaluation methods which influence comparability of the results; evaluating lesions under gastroscopic observation with strong subjectivity and influenced by many factors and conditions; lacks of methodological basis when evaluating symptoms and Chinese medicine syndromes; lack of evaluation of quality of life,etc. Aiming at these problems,the authors propose combinated evaluation of disease therapeutic effect and Chinese medicine syndrome effect and establish comprehensive evaluation system of histopathological indexes as core,combined with gastroscopic indexes,patients＇ symptoms,quality of life and other indexes.
出处
《中医杂志》
CSCD
北大核心
2015年第23期2013-2016,共4页
Journal of Traditional Chinese Medicine
基金
国家自然科学基金(81302955)
北京市科学技术委员会"首都临床特色应用研究"(Z141107002514018)
关键词
胃癌前病变
疗效评价
中医药疗法
precancerous lesions of gastric cancer
therapeutic evaluation
Chinese medicine therapy
