摘要
目的观察垂宁方治疗泌乳素(PRL)型垂体腺瘤的临床疗效。方法将176例PRL型垂体腺瘤患者随机分为2组,分别接受垂宁方联合溴隐亭和单纯溴隐亭治疗,比较PRL水平、治愈率、有效率和不良反应发生率等差异。结果 2组治疗后3、6、9、12个月PRL水平均较治疗前下降,差异有统计学意义(P<0.05)。2组PRL水平在治疗后3、6、9、12个月组间差异均有统计学意义(P<0.05);2组治愈率、有效率差异亦有统计学意义(P<0.05)。结论垂宁方联合溴隐亭降低血泌乳素水平安全有效。
Objective To observe the clinical effect of Chuining Prescription on the treatment of prolactin （PRL） pituitary adenoma. Methods 176 PRL pituitary adenoma patients were randomly divided into 2 groups which were treated respectively with the combination Chuining Prescription and Bromocriptine and Bromocriptine only, and the difference in PRL levels, curative rate, effective rate and adverse reaction rate were compared.Results The levels of PRL in 3, 6, 9 and 12 months after the treatment between two groups were significantly lower than those before the treatment, and the difference was statistically significant （ P 〈 0. 05 ） . The difference of PRL level in 3, 6, 9 and 12 months after the treatment between two groups was statistically significant （ P 〈 0. 05 ） ; the difference of cure rate and effective rate of two groups was statistically significant （ P 〈 0. 05 ）. Conclusion The combination of Chuining Prescription and Bromocriptine can decrease prolactin level with safety and efficacy.
出处
《北京中医药》
2015年第10期775-777,共3页
Beijing Journal of Traditional Chinese Medicine
基金
国家自然基金面上项目(81273732/H2708)
岳阳医院第七批青苗人才培养项目
关键词
垂体腺瘤
泌乳素
溴隐亭
中医药治疗
pituitary adenoma
prolactin
Bromocriptine
TCM treatment
