摘要
目的 探讨影响胰腺癌手术风险因素,总结经验教训以提高胰腺癌诊治水平.方法 回顾性分析187例胰腺癌手术病人的临床资料.选取18项可能影响胰腺癌围手术期死亡和术后并发症的相关因素,数据采用Logistic回归及Х^2检验进行统计学分析,筛选出影响胰腺癌围手术期死亡和术后并发症的危险因素.结果 围手术期死亡18例,发生术后并发症者73例.影响围手术期死亡的危险因素是年龄、肝功能Child-Pugh分级、非计划再次手术,影响围手术期术后并发症的危险因素是年龄、肝功能分级、手术方式、肿瘤分期.结论 胰腺癌围手术期风险是多因素综合作用的结果,年龄、肝脏储备功能是影响胰腺癌围手术期风险的独立危险因素,其中年龄大于60岁及肝功能Child-Pugh分级C级的病人,胰腺癌围手术期死亡和术后并发症的发生率显著升高.
Objective To investigate the perioperative risks of patients with pancreatic cancer to increase the levels of diagnosis and treatment for pancreatic cancer. Methods The clinical data of 187 patients with pancreatic cancer undergoing surgical treatments were retrospectively analyzed. Eighteen kinds of related factors probably influencing the pancreatic cancer perioperative death and postoperative complications were selected, and the data were statistically analyzed with Logistic regression and Chisquare test. The independent risk factors for perioperative death and postoperative complications of pancreatic cancer patients were screened out. Results There were 18 perioperative deaths, and postoperative complications occurred in 73 cases. The independent risk factors influencing the perioperative death were age, Child-Pugh score, and unplanned reoperation, etc. , and those for perioperative com- plications were age, Child-Pugh score, surgical procedures, tumor staging, etc. Conclusions Perioperative risks of pancreatic cancer result from the combined action by multiple factors. Above 60 years old, poor liver reserve function, unplanned reoperation, surgical method, and tumor staging are independent risk factors influencing the perioperative death and postoperative complications in pancreatic cancer patients.
出处
《腹部外科》
2015年第5期342-345,349,共5页
Journal of Abdominal Surgery
基金
国家国际科技合作专项（2014DFA31420）
贵州省科学技术厅社发攻关项目（黔科合SY字2015-3047）
关键词
胰腺癌
围手术期
危险因素
回顾性分析
Pancreatic eancer
Perioperative period
Risk factors
Retrospective analysis
