摘要
目的观察新鲜羊膜与生物羊膜治疗糖尿病患者翼状胬肉的疗效。方法 62例(64眼)患有糖尿病的翼状胬肉患者随机分为两组,每组31例(32眼),分别行新鲜羊膜移植(A组)和生物羊膜移植(B组)。术后两周、1月、6月、1年观察两组的术后视力,羊膜植片成活、角膜修复、翼状胬肉复发情况以及术后并发症。结果术后两组视力均较术前有提高,差异有统计学意义(P<0.05),术后两组视力比较差异无统计学意义(P>0.05)。术后角膜创面愈合时间A组(6.17±0.75)d,B组(6.27±0.71)d,两组比较差异无统计学意义(P>0.05)。A组1眼复发,复发率3.1%,B组2眼复发,复发率6.3%,两组复发率比较差异无统计学意义(P>0.05)。两组患者均未出现感染、植片排斥、提前溶解等并发症。结论新鲜羊膜与生物羊膜均可有效治疗糖尿病患者的翼状胬肉,二者疗效比较差异无统计学意义。
0bjective：To observe the clinical efficacy of diabetic patients with pterygium limbal by using fresh amnion or biological amnion. Methods：Sixty-two cases（64 eyes）with diabetic pterygium were randomly divided into two groups, and each group had 32 eyes. Group A received transplantation of fresh amnion followed by excision of pterygium,and group B were subjected to biological amnion transplantation followed by excision of pterygium. All the patients were followed up for 2 weeks,1 month,6 months and 1 year after surgery,and the visual acuity,graft survival,recurrence and complications were observed and compared. Results：The postoperative visual acuity of both of the groups improved significantly（ P﹤0. 05）. There was no significant difference between the two groups in postoperative visual acuity（P﹥0. 05）. The corneal epithelium healing was at（6. 17 ± 0. 75）day in the fresh amnion group,while at（6. 27 ± 0. 71）day in the biological am-nion group. The difference was not statistically significant between the two groups（P﹥0. 05）. One eye recurrence was not-ed in the fresh amnion group,and the recurrence rate was 3. 1%. Two eyes recurrence was noted in the biological amnion group,and the recurrence rate was 6. 3%. The difference was not statistically significant between the two groups（ P ﹥0. 05 ）. Conclusion：Both fresh amnion and biological amnion transplantation can be effective in the treatment of diabetic pa-tients with pterygium,and there is no significant difference between the two methods.
出处
《泰山医学院学报》
CAS
2015年第9期1004-1006,共3页
Journal of Taishan Medical College
关键词
糖尿病
翼状胬肉
羊膜移植
diabetic
pterygium
amnion transplantation
