摘要
多不饱和脂肪酸(polysaturated fatty acid,PUFA)是一类重要的脂肪酸族营养素,广泛参与细胞代谢和细胞膜脂的构成。在脑组织中,PUFA含量丰富,对促进大脑发育、增强学习记忆能力有重要作用,因而广受关注。本文综述PUFA的膳食来源及其与脑组织中磷脂构成的关系,以及PUFA参与大脑发育、影响大脑功能的作用机制,为确定膳食中ω-6/ω-3 PUFA的合理配比,科学添加源于深海鱼油和水藻的二十碳五烯酸(eicosapentaenoic acid,EPA)、二十二碳六烯酸(docosahexaenoic acid,DHA)或相关替代品,改善我国居民膳食中ω-3 PUFA的摄入不足,维持大脑健康功能提供理论依据。
Polyunsaturated fatty acids（PUFAs） are a group of important nutritional fatty acids which are involved in cell metabolism and plasma membrane constitution. PUFAs have attracted tremendous attention as an abundant component of brain tissue which plays a crucial role in brain development and improvement of learning and memory abilities. Herein, we summarize the relationship between dietary sources of PUFAs and brain phospholipid composition. Furthermore, the mechanisms of PUFAs on brain development and function are reviewed, which will provide a theoretical basis for the modification of dietary ω-6/ω-3 PUFA ratio in China via adding docosahexaenoic acid（DHA）, eicosapentaenoic acid（EPA） or related substitutes from deep-sea fish oil and algae.
出处
《食品科学》
EI
CAS
CSCD
北大核心
2015年第21期284-290,共7页
Food Science
基金
国家自然科学基金面上项目(31271855)
国家自然科学基金青年科学基金项目(31000772
81402669)
湖北省自然科学基金项目(2014CFB887)
湖北省教育厅科学技术研究项目(D20141705)
关键词
多不饱和脂肪酸
磷脂
大脑发育
大脑功能
polyunsaturated fatty acid
phospholipid
brain development
brain function
