摘要
目的探讨甲氨蝶吟与米非司酮的联合应用与单纯应用甲氨蝶吟对异位妊娠的临床治疗效果及护理方法。方法将该院2013年1月—2014年12月收治120例异位妊娠患者随机分为对照组和观察组各60例,两组均给予单次50 mg/m2肌肉注射甲氨蝶吟并服用米非司酮50 mg,连续给药6 d。对照组使用常规护理方式进行护理,观察组在常规护理基础上使用精心护理方式进行护理。观察两组患者的常规指标变化,比较治疗前后包块大小、血β-HCG含量,对比住院时间长短。结果观察组患者治疗后包块大小明显小于对照组、血β-HCG水平明显低于对照组,平均住院时间明显短于对照组;观察组患者发生不良反应率为8%,对照组为11%,组间比较差异无统计学意义。结论在异位妊娠的治疗上选用甲氨蝶呤与米非司酮联合治疗可以显著提高临床疗效,精心的护理可明显降低药物的不良反应,保障患者的恢复,是临床上值得广泛推广治疗方法。
Objective Armour ammonia butterfly Yin and mifepristone combined with simple application armour ammonia butterfly sing the clinical therapeutic effect of ectopic pregnancy and nursing methods. Methods To our hospital between January 2013 and December 2013, 120 patients with ectopic pregnancy were randomly divided into control group and observation group and control group, 60 cases in the two groups were given a single 50 mg/m2 intramuscular methotrexate butterfly Yin and taking mifepristone50 mg, continuous dosing 6 d. The control group using conventional nursing care in the form of group on the basis of conventional nursing use carefully nursing manner. Observed two groups of patients with conventional index changes, compared before and after treatment package block size and blood beta HCG levels, length of hospitalization. Results Observation group of patients after treatment package block sizes are much smaller than the control group, blood beta HCG levels significantly lower than the control group, the average hospitalization time obviously shorter than the control group; Observation group of patients with adverse reaction rate was 8%, the control group was 11%, there was no statistically significant difference between groups compare. Conclusion In the treatment of ectopic pregnancy to choose combination treatment with methotrexate and mifepristone can significantly improve the clinical curative effect, careful nursing can obviously reduce the adverse reaction of drugs, to ensure the patient's recovery, is worth popularizing widely clinical treatment.
出处
《中外医疗》
2015年第22期117-119,共3页
China & Foreign Medical Treatment
关键词
异位妊娠
甲氨蝶呤
米非司酮
护理效果
Ectopic Pregnancy
Methotrexate
Mifepristone
Clinical Efficacy