摘要
目的探讨激素替代疗法治疗围绝经期综合征妇女的疗效及对血雌二醇(E2)、卵泡刺激素(FSH)水平的影响。方法随机选取2013年5月—2015年1月该院收治的110例围绝经期综合征妇女作为研究对象,采用随机数字表法将所选患者分为研究组和对照组,每组各55例,研究组给予激素替代疗法治疗,对照组给予常规对症治疗。综合比较两组患者治疗总有效率、治疗前后血清E2、FSH变化情况及不良反应。结果研究组治疗总有效率为94.5%,高于对照组的80.0%(P<0.05);治疗后研究组患者血清E2水平升高,FSH水平降低,改善程度优于对照组(P<0.05);两组患者均无严重不良反应发生,耐受性好。结论激素替代疗法治疗围绝经期综合征妇女效果确切,安全性高,可显著改善患者的血E2、FSH水平。
Objective To investigate the effect of hormone replacement therapy for climacteric syndrome and the influence on blood E2,FSH level. Methods 110 cases of climacteric syndrome in our hospital, were randomly divided into research group and control group, each with 55 cases. Research group were treated with hormone replacement therapy. Control group were treated with conventional symptomatic treatment. Total effective rate, serum E2,FSH changes before and after treatment and adverse reactions were compared. Results Total effective rate of research group was 94.5%,which was higher than 80.0% of control group（P〈0.05）.After treatment, serum E2 levels of research group elevated, FSH levels declined, the degree of improvement were better than the control group（P〈0.05）. Both of two groups had no serious adverse reactions. Conclusion Hormone replacement therapy for climacteric syndrome is effective and safety. It could significantly improve level of serum E2, FSH.
出处
《中外医疗》
2015年第22期138-139,共2页
China & Foreign Medical Treatment
关键词
激素替代
围绝经期综合征
临床疗效
Hormone replacement therapy
Climacteric syndrome
Clinical efficacy
