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EMILIN蛋白家族与肿瘤的研究进展 被引量：1

EMILIN protein family and tumor: recent advances
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摘要 EMILIN蛋白家族是一类细胞外基质糖蛋白,参与维持机体组织器官形态与功能的稳态。新近研究表明,EMILIN可能通过激活某些信号传导通路参与调控肿瘤细胞凋亡和血管新生,在肿瘤生长和侵袭转移过程中发挥关键作用。笔者对其研究进展进行扼要综述。 EMILIN protein family consists of extracellular matrix glycoproteins that participate in maintenance of the structure and function of the organism.Recent studies suggest that EMILIN protein family potentially involves in tumor apoptosis and angiogenesis activating certain signal pathways,and plays a critical role in tumor growth,invasion and metastasis.The authors address the recent research progress in EMILIN protein family.
作者 林峰 陶一明 王志明
机构地区 中南大学湘雅医院普通外科
出处 《中国普通外科杂志》 CAS CSCD 北大核心 2015年第11期1609-1612,共4页 China Journal of General Surgery
基金 国家自然科学基金面上基金资助项目(81372630 81372631) 中南大学湘雅医院2014年度临床科研基金资助项目(2014L07)
关键词 肿瘤 EMILIN 细胞凋亡 新生血管化 病理性 综述文献 Neoplasms EMILIN Apoptosis Neovascularization Pathologic Review
分类号 R730 [医药卫生—肿瘤]
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参考文献37

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  • 2Bressan GM, Daga-Gordini D, Colombatti A, et al. Emilin, a component of elastic fibers preferentially located at the elastin- microfibrils interface[J]. J Cell Biol, 1993, 121(1):201-212.
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中国普通外科杂志
2015年 第11期

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