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脑苷肌肽治疗急性脑梗死的疗效及对血清基质金属蛋白酶-7水平的影响

The efficacy of cattle encephalon glycoside and ignotin in the treatment of acute cerebral infarction and its influence on serum matrix metalloproteinase 7
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摘要 目的探讨脑苷肌肽注射液治疗急性脑梗死患者的临床效果及对血清基质金属蛋白酶7(MMP-7)水平的影响。方法选取我院住院治疗的急性脑梗死患者70例,随机均分为2组,分别行常规治疗与脑苷肌肽治疗,对比2组疗效与MMP-7水平。结果治疗3周后观察组治疗有效率显著高于对照组,NIHSS评分与血清MMP-7水平显著低于对照组。结论脑苷肌肽注射液能够有效改善患者神经功能缺损情况,并有效降低患者血清基质蛋白酶水平。 Objective To observe the clinical effect of cattle encephalon glycoside and ignotin injection on acute cerebral in‐farction and serum matrix metalloproteinase 7(MMP‐7).Methods 70 cases with acute cerebral infarction treated in our hospital were selected and randomly divided into two groups. Patients in two groups separately received routine treatment and the thera‐py of encephalon glycoside and ignotin. The efficacy and MMP‐7 level of two groups were compared.Results After 3 weeks treatment ,the effective rate of the observation group was evidently higher than that of the control group ,and NIHSS scores and serum matrix MMP‐7 level of the observation group were significantly lower than that of the control group. Conclusion Cattle encephalon glycoside and ignotin injection not only can effectively treat acute cerebral infarction and improve neurologic impairment ,but also effectively reduce serum matrix metalloproteinase level.
作者 李玉文
出处 《中国实用神经疾病杂志》 2015年第20期16-17,共2页 Chinese Journal of Practical Nervous Diseases
关键词 脑苷肌肽 急性脑梗死 血清 基质金属蛋白酶7 Cattle encephalon glycoside and ignotin Acute cerebral infarction Serum
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