期刊文献+

蛛网膜下腔出血炎症反应与血管痉挛和脑损伤的关系 被引量:1

下载PDF
导出
摘要 蛛网膜下腔出血(SAH)可引起严重的神经系统并发症,但用于并发症治疗的药物有限。研究提示炎症是引起SAH后病理改变的始动因素,炎症直接引起血管痉挛和损伤,损伤和血管痉挛反过来导致缺血性脑损害。临床试验发现出血的早期损伤与晚期炎症反应之间关系复杂,抗炎治疗的不尽人意提示SAH的炎症反应受遗传和环境因素的影响,此外,SAH后的全身炎症反应也能诱发脑损伤和血管痉挛,本文就SAH后的炎症反应与血管痉挛和脑损伤的关系做一综述。
机构地区 解放军第
出处 《中国实用神经疾病杂志》 2015年第20期116-117,共2页 Chinese Journal of Practical Nervous Diseases
  • 相关文献

参考文献11

  • 1Xie X,Wu X,Cui J,et al.Increase ICAM-1 and LFA-1 expression by cerebrospinal fluid of subarachnoid hemorrhage patients:involvement of TNF-a[J].Brain Res?2013,1512:89-96.
  • 2Hopkins SJ,McMahon CJ,Singh N,et al.Cerebrospinal fluid and plasm cytolines after subarachnoid hemorrhage:CSF inter-leukin-6 may be an early marker of infection[J].J Neuroin-flammation,2012,9:255-263.
  • 3Muroi C,Hugelshofer M,Seule M,et al.Correlation among systemic inflammatory parameter,occurrence of delayed neurological deficits,and outcome after aneurismal subarachnoid hemorrhage[J].Neurosurgery,2013,72(3):367-375.
  • 4Jia W,Wang R,Zhao J,et al.E-selectin expression increased in human ruptured cerebral aneurysm tissues[J].Can J Neurol Sci,2011,38(6):858-862.
  • 5Kooijman E,Nijboer CHt van Velthoven CT,et al.The rodent endovascular puncture model of subarachnoid hemorrhage:mechanisms of brain damage and therapeutic strategies[J].J Neuroinflammation,2014,11:2.
  • 6Jung CS,Lange B,Zimmermann M,et al.The CSF concentration of ADMA,but ET-1,is correlated with the occurrence and severity of cerebral vasospasm after subarachnoid hemorrhage[J].Neurosci Lett,2012,524(1);20-24.
  • 7Zhang C,Lee JY,Keep RE,et al.Brain edema formation and complement activation in a rat model of subarachnoid hemor-rhage[J].Acta Neurochir Suppl,2013,118:157-161.
  • 8Chang CZ,Wu SC,Lin CL,et al.Atorvastatin preconditioning attenuates the production of endothelin-1 and prevents experimental vasospasm in rats[J].Acta Neurochir(Wien),2010,152(8):1399-1406.
  • 9Macdonald RL.Delayed neurological deterioration after subarachnoid hemorrhage[J].Nat Rev Neurol,2014,10(1):44-58.
  • 10Murahashi T,Kamiyama K,Hara K,et al.The efficiency of cilostazol for cerebral vasospasm following subarachnoid hem-orrhage[J].No Shinkei Geka,2013,41(5):393-400.

同被引文献7

引证文献1

二级引证文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部