摘要
目的 研究阴茎皮瓣尿道成形术治疗前尿道狭窄的长期疗效情况.方法 选取2010年1月至2014年1月于本院接受治疗的80例前尿道狭窄患者,按数字表法随机将患者分为两组,每组各40例.其中观察组采用阴茎皮瓣尿道成形术进行治疗,对照组采用口腔黏膜尿道成形术进行治疗,观察并对比两组患者治疗后的远期疗效以及不良反应等情况.结果 两组患者狭窄长度、术前治疗次数相比无显著性差异,在假性憩室方面观察组要显著低于对照组,差异有统计学意义（P＜0.05）.两组患者手术时间、术中出血量、拔出尿管时间均无显著差异（P＜0.05）;观察组皮瓣成活率达到100％明显高于对照组80.0％,患者拔除尿管时及术后3个月最大尿流率（MFR）、国际前列腺症状评分（IPSS）均明显优于对照组（P＜0.05）;术后随访1年,观察组不良反应发生率明显低于对照组（P＜0.05）;观察组患者治疗后1年QOL评分显著高于对照组,差异有统计学意义（P＜0.05）.结论 相对口腔黏膜尿道成形术,使用阴茎皮瓣尿道成形术治前尿道狭窄具有较为显著的疗效,患者远期恢复情况较好,且皮瓣成活率、不良反应情况均较少,是治疗前尿道狭窄十分有效的治疗方法。
Objectives To explore long-term efficacy of Penile skin flap urethroplasty surgery in the treatment of anterior urethral stricture.Methods From January 2010 to January 2014 in our hospital 80 cases of anterior urethral stricture patients,were randomly divided into two groups,40 cases in each group.The observation group with penis skin flap urethroplasty for treatment,control group with oral mucosaurethroplasty for treatment,observation of long term efficacy of the two groups after treatment and adverse reaction conditions.Results two groups of patients before treatment the symptom integral had no significant difference after treatment,the observation group were significantly lower than those in the control group,the difference was statistically significant,P 〈 0.05;Two groups of patients with operation time,intraoperative bleeding volume,and there were no significant differences in the catheter time,P 〉0.05;The observation group the survival rate of 100% was significantly higher than the control group of 80% patients,the maximal urinary flow rate（MFR）,the International Prostate Symptom Score （IPSS） was significantly better than the control group at 3 months and pulling out the catheter after operation,P 〈0.05;adverse reaction rate of observation group was significantly lower than the control group in the 1 years after the operation,P 〈 0.05;Patients in the observation group 1 years after treatment QOL score was significantly higher than that of control group,difference had statistical significance,P 〈 0.05.Conclusions For patients with penile skin flap urethroplasty in the treatment of anterior urethral stricture had more significant effect in patients with long-termrecovery,better than the oral mucosa urethroplasty,and the flap survival rate,adverse reactions are less,is the treatment of anterior urethral stricture treatment method is very effective.
出处
《国际泌尿系统杂志》
2015年第6期843-846,共4页
International Journal of Urology and Nephrology
关键词
尿道狭窄
阴茎
外科皮瓣
Urethral Stricture
Penis
Surgical Flaps
