摘要
目的探讨呋塞米片治疗肺心病急性加重期的临床疗效。方法选取2012年5月—2015年4月北海市中医医院收治的肺心病急性加重期患者67例,根据治疗方案不同分为观察组(36例)与对照组(31例)。对照组患者予以常规治疗,观察组在对照组基础上予以呋塞米片治疗。观察两组患者临床疗效、治疗前后左心室射血分数(LVEF)及不良反应发生情况。结果观察组患者临床疗效优于对照组,差异有统计学意义(P<0.05);治疗前两组患者LVEF比较,差异无统计学意义(P>0.05),治疗后观察组患者LVEF高于对照组,差异有统计学意义(P<0.05);两组患者均未发生严重不良反应。结论呋塞米片治疗肺心病急性加重期的临床疗效显著,可改善患者心功能,且不良反应少。
Objective To explore the effect of furosemide in treating acute exacerbation of cor pulmonale. Methods A total of 67 patients with acute exacerbation of cor pulmonale were selected in the Chinese Medicine Hospital of Beihai from May 2012 to April 2015,according to the different treatment,they were divided into observation group（36 cases）and control group（31 cases）. Control group were given routine treatment,observation group were given furosemide treatment on the basis of control group. Clinical effect,before and after treatment left ventricular ejection fraction（LVEF）and incidence of adverse re-actions between the two groups were compared. Results Clinical effect of observation group was better than that of control group （P 〈 0. 05）;Before treatment,LVEF showed no significant differences between the two groups（P 〉 0. 05）,LVEF of observa-tion group was higher than that of control group after treatment（P 〈 0. 05）;no one of the two groups occurred serious adverse reactions. Conclusion Furosemide has notable curative effect in the treatment of acute exacerbation of cor pulmonale,can im-prove cardiac function and has less adverse reactions.
出处
《临床合理用药杂志》
2015年第33期56-57,共2页
Chinese Journal of Clinical Rational Drug Use
关键词
肺心病
呋塞米
治疗结果
Pulmonary heart disease
Furosemide
Treatment outcome
