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2011~2014年杭州部分地区儿童感染肺炎链球菌的耐药性变迁 被引量:1

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摘要 目的 了解肺炎链球菌(SPN)在杭州地区儿童中的感染情况及其耐药性变迁,为临床合理用药提供参考.方法 对2011年1月至2014年12月分离的127株SPN进行11种抗菌药的药敏测定.结果 检出SPN的患儿以婴儿最多(85.8%),气管吸出物检出率高(31.0‰).127株SPN对红霉素、克林霉素、四环素、复方新诺明耐药率高,分别为96.1%、85.0%、74.0%、66.1%,对青霉素、阿莫西林、氯霉素、头孢噻肟耐药率低,分别为0.8%、1.7%、8.0%、9.3%;未检出对奎奴普丁-迭福普丁、左氧氟沙星和万古霉素耐药的菌株.结论 本地区SPN对多种临床常用抗生素耐药性强,对青霉素类仍较敏感,青霉素类和头孢类可作为经验用药的首选药物.临床应根据药敏结果和患儿病情,合理选用抗菌药.
机构地区 杭州市儿童医院
出处 《浙江临床医学》 2015年第12期2129-2130,共2页 Zhejiang Clinical Medical Journal
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