摘要
目的 观察和比较采用奥卡西平和卡马西平对原发性三叉神经痛进行治疗的临床疗效. 方法 选取永煤集团总医院2012年5月至2014年5月124例原发性三叉神经痛患者,并随机将所选取的患者分为两组,观察组单纯采用奥卡西平进行治疗,对照组单纯采用卡马西平进行治疗. 对两组患者的临床疗效进行观察和对比.结果 在治疗1周和治疗2个月后,两组患者神经疼痛的视觉模拟评分（VSA）比较差异有统计学意义（P〈0.05）;观察组不良反应发生率低于对照组,且差异有统计学意义（ P〈0.05 ）. 结论 对原发性三叉神经痛的临床疗效,奥卡西平明显比卡马西平好,且奥卡西平的不良反应更轻,值得在临床上推广.
Objective To observe and compare the clinical efficacy of oxcarbazepine and carbamazepine on prima -ry trigeminal neuralgia .Methods Selected 124 cases of trigeminal neuralgia from May 2012 to 2014 May, and randomly divided them into two groups .The 64 patients in observation group used oxcarbazepine treatment merely , and 60 patients in the control group used carbamazepine treatment merely .Then the clinical efficacy of the two groups were observed and com-pared.Results After treatment for one week and two months , there was significant difference in nerve pain visual ana-logue scale （ VSA） （ P〈0.05）;the adverse reaction rate in observation group was significantly lower than that in the con-trol group （P〈0.05）.Conclusions The clinical efficacy of oxcarbazepine is significantly better than carbamazepine on primary trigeminal neuralgia , with less adverse reactions ,so it is worthy of being promoted in clinical practice .
出处
《中国实用医刊》
2015年第23期71-72,共2页
Chinese Journal of Practical Medicine
