摘要
目的探讨吸入用布地奈德混悬液联合硫酸沙丁胺醇气雾剂雾化吸入治疗急性期COPD的临床效果。方法选取2013年1月-2015年1月本院收治的112例急性期COPD患者作为研究对象,随机分为观察组及对照组,各56例。在常规治疗基础上,对照组给予硫酸沙丁胺醇气雾剂雾化吸入,静脉滴注甲基泼尼松龙治疗;观察组给予吸入用布地奈德混悬液联合硫酸沙丁胺醇气雾剂雾化吸入治疗。比较两组的疗效。结果观察组的总有效率显著高于对照组,差异有统计学意义（P〈0.05）。两组治疗后的肺功能及动脉血气水平显著优于治疗前,差异有统计学意义（P〈0.05）。两组治疗后的肺功能及动脉血气水平比较,差异无统计学意义（P〉0.05）。观察组的不良反应发生率显著低于对照组,差异有统计学意义（P〈0.05）。结论吸入用布地奈德混悬液联合硫酸沙丁胺醇气雾剂雾化吸入治疗急性期COPD效果显著,不良反应少。
Objective To explore the clinical effect of budesonide suspension combined with salbutamol aerosol for inhalation in the treatment of acute exacerbation of chronic obstructive pulmonary disease（COPD）. Methods 112 patients with acute COPD from January 2013 to January 2015 in our hospital were selected and randomly divided into the observation group and the control group,56 cases in each group.On the basis of routine treatment,the control group was given salbutamol aerosol for inhalation and methyl prednisolone for intravenous injection treatment,the observation group was given budesonide suspension and salbutamol aerosol for inhalation treatment.The efficacy in two groups was compared. Results The total effective rate of the observation group was higher than that of the control group,with significant difference（P〈0.05）.The level of pulmonary function and arterial blood gas in two groups after treatment was better than that before treatment,with significant difference（P〈0.05）.There was no significant difference in the level of pulmonary function and arterial blood gas between two groups（P〉0.05）.The incidence rate of adverse reaction in the observation group was lower than that of the control group,with significant difference（P〈0.05）. Conclusion Budesonide suspension combined with salbutamol aerosol for inhalation in the treatment of acute COPD has exact curative effect and less adverse reaction.
出处
《中国当代医药》
2015年第33期38-40,共3页
China Modern Medicine
