摘要
目的分析消化科住院患者医院感染的病原菌分布及耐药性,为临床有效的经验性用药提供参考依据。方法选择2014年3月-2015年3月于医院消化科就诊的880例患者,分析患者感染病原菌的分布及药敏试验结果,数据采用SPSS 13.0软件进行统计分析。结果感染患者共96例,感染率为10.91%;以消化系统感染为主,共35例占36.46%;96例感染患者共检出121株病原菌,以革兰阴性菌为主,共72株占59.51%;革兰阴性菌主要为大肠埃希菌、肺炎克雷伯菌,分别占24.79%、11.57%;大肠埃希菌对头孢哌酮/舒巴坦、亚胺培南及头孢哌酮/舒巴坦较敏感,敏感率均>70.00%,肠球菌属、金黄色葡萄球菌对万古霉素较敏感,敏感率均>79.00%。结论消化科住院患者相对感染率低,以消化系统感染为主,常见病原菌为革兰阴性菌,经验性用药可以考虑碳青霉烯类抗菌药物。
OBJECTIVE To analyze the pathogen distribution and drug resistance of hospital infections in gastroen- terology hospitalized patients, so as to provide evidence for clinical empirical medicine. METHODS Totally 880 pa- tients were selected from Mar. 2014 to Mar. 2015 in our hospital of gastroenterology department, and distribution of culture bacteria and drug susceptibility test results were analyzed. SPSS 13.0 was adopted for statistical analy- sis. RESULTS Among the 880 cases of gastroenterology hospitalized patients, 96 cases were found to be infected and the infection rate was 10.91%. Digestion system was found to be the most susceptible sites with 35 cases ac- counting for 36.46%. Totally 121 strains of pathogens were detected, including 72 （59.51%） strains of gram- negative bacteria, which accounted for the majority. The gram-negative mainly included Escherichia coli and Klebsiella pneumoniae, respectively, 24.79% and 11.57%. Escherichia coli were proved to be sensitive to cef- operazone/sulbactam and imipenem and the sensitivity rate were all over 70.00%. Enterococcus and Staphylococ- cus aureus were more sensitive to vaneomyein with the sensitivity rate over 79.00%. CONCLUSION The infection rate in the digestive department is are the common pathogens in the relatively low and it mainly happens department and earbapenems can be in digestion system. Gram-negative bacteria considered as empirical medication.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2015年第23期5332-5334,共3页
Chinese Journal of Nosocomiology
基金
浙江省自然科学基金资助项目(Z2015034672)
关键词
消化科
医院感染
病原菌
耐药性
Gastroenterology
Hospital infection
Pathogens
Drug resistance
