摘要
目的通过超声心动图及冠状动脉造影的检查，探讨心外膜脂肪组织厚度（EAT）与冠心病的关系。方法选择我院拟诊为冠心病的住院患者164例，均经过超声心动图及冠状动脉造影术检查。根据冠状动脉造影术检查，将其分成冠心病组81例及非冠心病组（对照组）83例。结果两组在年龄、性别、高血压病史、糖尿病史、吸烟史上比较差异无统计学意义（P〉0．05）；冠心病组总胆固醇（TC）、甘油三酯（TG）、高密度脂蛋白胆固醇（HDL、C）、低密度脂蛋白胆固醇（LDL～C）和血清脂蛋白（a）[LP（a）]与对照组比较差异有统计学意义（P〈0．05），血糖差异则无统计学意义（P〉0．05）。经胸彩色多普勒超声心动图检查：冠心病组心外膜脂肪组织厚度（EAT）与对照组比较差异有统计学意义（P〈0．05），其诊断冠心病存在的受试者工作特征曲线（ROC）下面积为0．763，95％CI为0．69—0．84，诊断切点值为0．55em；诊断敏感度为62％，特异度为84％。结论心外膜脂肪组织厚度（EAT）与冠心病有一定的相关性，可通过对患者经胸心脏超声的无创检查，结合病史及实验室检查，对高危患者起到一定的筛查作用。
Objective To explore the relationship between thickness of epicardial adipose thick- ness（EAT） and coronary heart disease（CHD） by echocardiography and coronary angiography（CAG）. Methods 164 cases of suspected CHD were enrolled. Each of them had examinations of echocardio- graphy and coronary angiography. According to the result of coronary angiography examination, patients were divided into two groups,CHD group（81 cases） and control group（83 cases）. Results There is no statistical difference between two groups in age, gender, history of hypertension, diabetes and smoking his- tory（ P 〉 0.05 ）. Comparing to control group ,TG, TC, HDL-C, LDL-C and LP（a） were significant higher in CHD group（ P 〈0.05 ） ,and there is no statistical difference between two groups in blood sugar（P 〉0.05 ）. The EAT was significant higher in CHD group（ P 〈 0.05 ） by echocardiography and area under ROC curve of EAT measured by transthoracic echoeardiography in the diagnosis of CHD was 0. 763,95% CI for 0.694）. 84,appropriate cut of was 0. 55 cm. The diagnostic sensitivity was 62% and the diagnostic specificity was 84%. Conclusion There was a relationship between EAT and CHD,EAT combining with histories and laboratory tests can screen the patients with high risk of CHD.
出处
《临床内科杂志》
CAS
2015年第11期742-744,共3页
Journal of Clinical Internal Medicine
