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三维超声容积自动测量技术评价胎儿小脑蚓部的临床价值 被引量:2

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摘要 目的应用三维超声容积自动测量技术(VOCAL)测量胎儿小脑蚓部并研究产前诊断胎儿小脑蚓部异常的临床价值。方法对2010年~2014年41 173例孕24~26W的胎儿应用腹部三维超声容积探头,在胎头小脑蚓部的正中矢状切面,测量胎儿小脑蚓部面积,再应用三维超声的容积测量技术(virtual organ computer aided analysis,VOCAL)对24~26w胎儿进行小脑蚓部体积的计算。结果胎儿小脑蚓部体积与孕周呈正相关(r=0.86,P〈0.05),从中发现胎儿小脑蚓部异常Dandy-Walker综合征8例,均接受胎儿羊水或脐血行染色体检查,发现染色体异常5例,其中13-三体2例,18-三体3例。所有异常病例均选择终止妊娠并行尸检证实。结论三维超声体积自动测量技术能够测量胎儿小脑蚓部体积,可作为超声评价胎儿小脑蚓部发育及评价异常的一项可靠有效指标。
出处 《中国优生与遗传杂志》 2015年第12期84-84,82,共2页 Chinese Journal of Birth Health & Heredity
基金 绍兴市科技局项目(2008A33008)
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参考文献6

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