摘要
目的:探讨复杂性热性惊厥脑电图特征与癫痫发生的相关性。方法:2012年3月到2014年5月选择在我院诊治为复杂性热性惊厥的呼吸道感染患儿86例作为观察组,同期选择在我院诊治的非热性惊厥的呼吸道感染患儿86例作为对照组,两组都进行脑电图监测与认知功能判定,对癫痫发生情况进行判定与分析。结果:观察组的言语智商、行为智商与总智商评分都明显低于对照组(P<0.05)。观察组的癫痫发生率为9.3%,脑电图异常率为8.1%;而对照组的癫痫发生率为1.2%,脑电图异常率为2.3%,对比差异都有统计学意义(P<0.05)。在观察组患儿中,Spearman相关性分析显示脑电图异常与癫痫发生存在明显正向相关性(r=0.349,P<0.05)。结论:复杂性热性惊厥伴随有脑电图异常,与癫痫发生存在明显正向相关性,损害患儿的认知功能。
Objective: To investigate the correlation between epilepsy and EEG features in complex febrile seizures. Methods: 86 cases of respiratory tract infections with complex febrile seizures in children were selected from March 2012 to May 2014 in our hospital for treatment as the observation group, and 86 cases of respiratory tract infections without febrile seizures in children were as the control group. Both groups were given EEG monitoring and cognitive function judgment of epilepsy determination and analysis of the situation. Results: The verbal IQ, behavior IQ and overall IQ scores in the observation group were significantly lower (P 〈0.05). The epilepsy and EEG abnormalities in the observation group were 9.3 % and 8.1%; while the control group were 1.2 % and 2.3 %, and the differences were statistically significant between two groups (P 〈0.05). Spearman correlation analysis showed significant positive abnormal EEG correlation with epilepsy (r = 0.349, P 〈0.05) in the observation group. Conclusions: Complex febrile seizures accompany by EEG abnormalities, have significant positive correlation with epilepsy, which can impair children's cognitive function.
出处
《现代生物医学进展》
CAS
2015年第34期6759-6761,共3页
Progress in Modern Biomedicine