摘要
目的探讨缺血性脑血管病与冠心病严重程度的相关性。方法选取神经内科新入院的老年患者260例,根据患者入院后头颅MRI及磁共振血管造影检查,对患者在缺血性脑血管病包括脑梗死、缺血性脑白质病和脑动脉粥样硬化三个方面的严重程度进行影像学评分;同时根据患者入院后所做的心电图检查及既往病史,对患者进行冠心病严重程度评分,然后将患者的影像学评分与冠心病评分进行关联分析。结果脑梗死、缺血性脑白质病及脑动脉粥样硬化评分与冠心病评分均无相关性(r=0.056,P=0.382;r=0.009,P=0.882;r=0.045,P=0.591)。在249例头颅MRI检查的患者中,确诊脑梗死153例(61.4%),无脑梗死96例(38.6%)。在260例心电图检查的患者中,依据心电图检查及冠心病史,确诊冠心病164例(63.1%),无冠心病96例(36.9%)。脑梗死与冠心病患病率比较,差异无统计学意义(P>0.05)。结论同一人群在缺血性脑血管病与冠心病患病及病情严重程度方面无相关性,说明缺血性脑血管病与冠心病在病因及发病机制方面存在明显不同,具体差异尚需进一步研究,在治疗和预防方面也应区别对待。
Objective To study the relation between ischemic cerebrovascular disease（ICVD）and coronary heart disease（CHD）.Methods Two hundred and sixty patients who underwent brain MRI and MRA in our hospital were included in this study.Ischemic stroke,ischemic leukoencephalopathy,cerebral atherosclerosis and CHD were scored.Relation between ICVD and CHD was analyzed.Results Ischemic stroke,ischemic leukoencephalopathy,cerebral atherosclerosis were not related with CHD（r=0.056,P=0.382;r=0.009,P=0.882;r=0.045,P=0.591）.Of the249 cases with MRI examination,153（61.4%）were identified with cerebral infarction and 96cases（38.6%）without.Of the 260 cases with ECG examination,164（63.1%）were identified with CHD and 96（36.9%）without,according to the ECG examination and the history of CHD.No significant difference was found in the prevalence of cerebral infarction and of CHD（P0.05）.Conclusion ICVD is not related with CHD in the same population,indicating that the etiology and pathogenesis of ICVD are significantly different from those of CHD,which should thus be further studied.
出处
《中华老年心脑血管病杂志》
CAS
2015年第12期1279-1281,共3页
Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
关键词
脑血管障碍
冠心病
脑梗死
动脉粥样硬化
磁共振成像
磁共振血管造影术
cerebrovascular disorders
coronary disease
brain infarction
atherosclerosis
magnetic resonance imaging
magnetic resonance angiography
