摘要
目的了解小榄地区妊娠早期妇女TORCH感染状况及其与不良孕产史的关系。方法选取南方医科大学附属小榄医院2013年7月-2014年7月TORCH筛查的9 578例妊娠早期妇女,采用电化学发光法及酶联免疫技术(捕获法)测定TORCH特异性抗体。结果小榄地区妊娠早期妇女CMV-Ig G(92.83%)和Rv-Ig G(79.68%)阳性率较高,其次为Tox-Ig G(8.06%);CMV-Ig M(0.5%),Rv-Ig M(0.40%)和Tox-Ig M(0.42%)阳性率之间差异无统计学意义,但均高于HSVII-Ig M阳性率(0.11%)(均P<0.05);不良孕产史妇女CMV-Ig G(98.61%)和Rv-Ig G(81.94)阳性率较高,其次为Tox-Ig G(9.72%),三者阳性率均高于初孕初产妇女(均P<0.05);正常孕产史妇女CMV-Ig G(95.34%),Rv-Ig G(80.23%)和Tox-Ig G(8.47%)阳性率均高于初孕初产妇女(均P<0.05);不良孕产史妇女CMV-Ig G阳性率高于正常孕产史妇女(P<0.05),两组之间Rv-Ig G阳性率和Tox-Ig G阳性率差异无统计学意义(均P>0.05)。结论小榄地区妊娠早期妇女尤其是不良孕产史妇女存在一定比例的TORCH感染,以巨细胞病毒(CMV)和风疹病毒(RV)感染为主,提示不良孕产史妇女是TORCH感染的高危人群,对不良孕产史妇女进行TORCH感染预防和监测,对生产健康优质胎儿具有重要意义。
Objective To investigate the prevalence of TORCH infection and its relationship with abnormal pregnancy historyin women with early pregnancy in Xiaolan region. Methods A total of 9,578 cases of early pregnant women were selectedfrom Xiaolan Hospital Affiliated to Southern Medical University from July 2013 to July 2014 to screen TORCH infection. Thespecific antibodies against TORCH were detected by ECLIA or ELISA （capture）. Results The positive rates of CMV- IgG（92.83%） and Rv - IgG（79.68% ） were higher, followed by that of Tox - IgG（8.06% ）. The txxsitive rates of CMV - IgM（0.5%）, Rv - IgM（0.40% ） and Tox - IgM （0.42%） in the early pregnant women showed no statistically significant differ-ence, but they were all higher than that of HSVII - IgM （0.11%, P 〈 0.05）. The positive rates of CMV - IgG （98.61% ）, Rv- IgG （81.94%） and Tox- IgG （9.72%） in women with abnormal pregnancy history were all higher than those in primiparas（all P 〈 0.05）. The positive rates of CMV- IgG （95.34 % ）, Rv - IgG （80.23 % ） ana Tox - IgG （8.47 % ） in women withnormal pregnancy history were all higher than those in primiparas （all P 〈 0.05 ）. The positive rate of CMV - IgG in womenwith abnormal pregnancy history was higher than that of women with normal pregnancy history （P 〈 0.05）, but no statisticallysignificant differences were found in the positive rates of Rv- IgG and Tox- IgG between the two groups （both P 〉0.05）.Conclusions Cytomegalovirus （CMV） and rubella virus （RV） infections are the prevailing types of TORCH infection amongearly pregnant women in Xiaolan region, especially in women with abnormal pregnancy history. Therefore, it is of great value toeugenics to prevent and monitor TORCH infection in women with abnormal pregnancy history.
出处
《实用预防医学》
CAS
2016年第1期64-66,共3页
Practical Preventive Medicine
基金
广东省中山市卫生局医学科研基金资助项目(2013J172)
