期刊文献+

老年人衰弱综合征的发病机制和评估及管理 被引量:51

Mechanism, assesment and management of frailty syndrome
原文传递
导出
摘要 随着全球老龄化和衰老与疾病相关研究的深入,衰弱已经成为现代老年医学研究的热点问题之一。衰弱是一种常见的重要老年综合征,表现为机体的脆弱性增加,维持稳态的能力下降,面对各种应激时,发病和死亡的风险增加。其核心特点是多个生理系统(神经肌肉、代谢及免疫系统等)的储备功能下降。
出处 《中华老年医学杂志》 CAS CSCD 北大核心 2015年第12期1282-1285,共4页 Chinese Journal of Geriatrics
基金 美国国家卫生研究院项目基金(R21-AG-043874,R01A1108907),厄玛和保罗米尔斯坦老年健康专项奖学金(Irma and Paul Milstein Program for Senior Health fellowship),米尔斯坦亚美医学基金会( Milstein Medical Asian American Partnership (MMAAP) Foundation)
关键词 衰弱 疾病管理 Frailty Disease management
  • 相关文献

参考文献17

  • 1Collard RM, Boter H, Schoevers RA, et al. Prevalence of frailty in community-dwelling older persons: a systematic review[J]. J Am Geriatr Soc, 2012, 60:1487-1492.
  • 2Chen X, Mao G, Leng SX. Frailty syndrome: an overview[J]. Clin Interv Aging, 2014, 9:433-441.
  • 3Franceschi C1, Bonaf: M, Valensin S, eta[. Inflamm-aging, an evolutionary perspective on immunosenescence[J]. Ann N Y Acad Sci, 2000, 908:244-254.
  • 4Cevenini El, Caruso C, Candore G, et al . Age- related inflammation: the contribution of different organs, tissues and systems. How to face it for therapeutic approaches [J] . Curr Pharm Des, 2010, 16:609-618.
  • 5Leng S, Chaves P, Koenig K, et al. Serum interleukin-6 and hemoglobin as physiological correlates in the geriatric syndrome of frailty: a pilot study[J]. J Am Geriatr Soc, 2002, 50:1268-1271.
  • 6Li H, Manwani B, Leng SX. Frailty, inflammation, and immunity[,J]. Aging Dis, 2011, 2:466-473.
  • 7Yao X, Li H, Leng SX. Inflammation and immune system alterations in frailty[J]. Clin Geriatr Med, 2011, 27:79-87.
  • 8Maggio M, Cappola AR, Ceda GP, et al. The hormonal pathway to frailty in older men [,J]. J Endocrinol Invest, 2005, 28 : 15-19.
  • 9Morley JE, Vellas B, van Kan GA, et al. Frailty consensus: a call to actionEJ]. J Am Med Dir Assoc, 2013, 14:392-397.
  • 10Jones DM, Song X, Rockwood K. Operationalizing a frailty index from a standardized comprehensive geriatric assessment[,J]. J Am Geriatr Soc, 2004,52: 1929-1933.

二级参考文献4

  • 1Qato DM, Alexander GC, Conti RM, et al. Use of prescription and over-the-counter medications and dietary supplements among older adults in the United States. JAMA, 2008, 300: 2867-2878.
  • 2Beers MH, Ouslander JG, Rollingher I, et al. Explicit criteria for determining inappropriate medication use in nursing home residents. UCLA Division of Geriatric Medicine. Arch Intern Med, 1991, 151: 1825-1832.
  • 3American Geriatrics Society 2012 Beers Criteria Update Expert Panel. American Geriatrics Society updated Beers Criteria for potentially inappropriate medication use in older adults. J Am Geriatr Soc, 2012, 60: 616-631.
  • 4沈杰,刘奕芳,高宁舟,宋钟娟.Beers判断标准在老年住院患者潜在性不适当用药评价中的应用[J].中国药房,2010,21(6):556-558. 被引量:53

共引文献31

同被引文献351

引证文献51

二级引证文献411

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部