摘要
以苦参水提液进行小鼠急性毒性实验,考察新鲜苦参和商品苦参水提液的毒性。结果商品苦参水提液LD_(50)为22.23 g/kg,其95%可信限为18.41-26.92 g/kg;新鲜苦参水提液LD_(50)为12.25 g/kg,其95%可信限为9.38-16.00 g/kg。表明新鲜苦参水提液毒性大于商品苦参水提液。
In order to understand the toxicity of water extraction of fresh Sophora flavescens and commodity one,acute toxicity test in mice was carried out with their water extraction.The results showed that LD_50 of commodity Sophora flavescens water extraction was 22.23 g/kg with 95%confidence limit of 18.41-26.92 g/kg;LD_50 of fresh Sophora flavescens water extraction was 12.25 g/kg with 95%confidence limit of 9.38-16.00 g/kg.That indicated fresh Sophora flavescens extract has more toxicity than commodity one.
出处
《中兽医医药杂志》
2015年第6期27-29,共3页
Journal of Traditional Chinese Veterinary Medicine
基金
江苏高校优势学科建设工程资助项目
关键词
苦参
小鼠
急性毒性
LD_50
Sophora flavescens
mice
acute toxicity
LD_50
