摘要
目的研究缺血性脑卒中与阻塞性睡眠呼吸暂停综合征(OSAS)的临床相关性。方法选取我院神经内科收治的缺血性脑卒中患者70例,分为伴发OSAS患者组(A组)31例和非OSAS的患者组(B组)39例。比较两组患者超敏C反应蛋白(hs-CRP)、同型半胱氨酸(HCY)、纤维蛋白原(Fg)水平、颈动脉内-中膜厚度(IMT)及斑块发生率。结果A组hs-CRP、HCY、Fg水平、颈动脉IMT及斑块发生率明显高于B组(P<0.05)。结论 OSAS是导致缺血性脑卒中的独立危险因素,炎症反应、高HCY血症、凝血异常等改变及其所致的动脉粥样硬化可能是OSAS导致缺血性脑卒中的机制。
Objective Studies of ischemie stroke and obstructive sleep apnea syndrome （OSAS） clinical relevance. Methods Elected department of neurology treated 70 cases of ischemic cere- bral apoplexy patients, divided into comorbid patients with OSAS group（group A） 31 cases and＇the patients with OSAS group 39 eases （group B）. Compare two groups of patients with allergic e-re- active protein（hs CRP） and homocysteine（HCY）, fibrinogen （Fg） level, the carotid artery in the film thickness （IMT） and plaque incidence. Results In group A of the hs - CRP, HCY, Fg levels and incidence of carotid artery iMT and plaques are significantly higher than group B （P〈0.05）. Conclusions OSAS was the independent risk factors of isehemic cerebral apoplexy, inflammatory reaction, high HCY levels, and coagulopathy atheroselerosis may be caused by a change and OSAS led to the mechanism of ischemic cerebral aDonlexv_
出处
《现代诊断与治疗》
CAS
2015年第20期4561-4563,共3页
Modern Diagnosis and Treatment
基金
江西省卫生厅2014年度科技计划项目(赣卫科教[2013]26号编号:20143251)
