右美托咪定和丙泊酚辅助硬膜外麻醉的镇静效果对比分析被引量：8

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摘要目的:比较右美托咪定(Dex)和丙泊酚辅助硬膜外麻醉的镇静效果。方法:选取2012年1月-2015年3月在我院接受硬膜外麻醉的80例妇科手术患者为观察对象,随机平均分成右美托咪定组(D组)与丙泊酚组(P组),每组40例。D组患者给右美托咪定辅助硬膜外麻醉,P组给予丙泊酚辅助硬膜外麻醉,比较两组患者在给药前(T0)、手术10min(T1)、手术30min(T2)以及手术结束后(T3)时的HR、MAP、SpO2以及Ramsay镇静评分情况。结果:(1)两组患者在T1、T2、T3时间点的HR及MAP均较T0时有明显降低(P<0.05),且P组患者的HR降低更为明显(P<0.05);两组患者的SpO2在手术前、后变化不大(P>0.05)。(2)两组患者在T1、T2、T3时的Ramsay镇静评分较T0时有明显升高(P<0.05),且D组患者的Ramsay镇静评分明显高于P组患者,两组比较差异有统计学意义(P<0.05)。结论:妇科手术患者实施硬膜外麻醉过程中给予右美托咪定辅助麻醉可有效稳定患者心跳和血压,镇静效果明显且不会产生明显的呼吸抑制,疗效安全、可靠,是一种临床安全、有效的辅助硬膜外麻醉药物。

作者罗冠贤黄广翔

机构地区广西贵港市中西医结合骨科医院

出处《医学理论与实践》 2015年第24期3391-3392,共2页 The Journal of Medical Theory and Practice

关键词右美托咪定丙泊酚硬膜外麻醉镇静效果

分类号 R614.42 [医药卫生—麻醉学]

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1李撰.右美托咪定、丙泊酚用于硬膜外麻醉妇科手术患者镇静的效果比较[J].中国医药科学,2012,2(23):110-111. 被引量：26
2芦相玉,王宏涛,王世端,李瑜.比较右美托咪定、丙泊酚、咪达唑仑辅助硬膜外麻醉镇静的效果[J].中国新药与临床杂志,2011,30(11):873-877. 被引量：50
3夏婧,王世端,黄辉,江岩,徐红梅,栾奇.右美托咪定与异丙酚用于硬膜外麻醉下老年患者髋关节置换术的镇静效果比较[J].中华临床医师杂志（电子版）,2013,7(4):196-197. 被引量：13

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